SCHEMBL1878393

SCHEMBL1878393

CC1CNc2cc(O)c(O)cc21

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.44
MAOA P21397 4/20 0.39
DRD2 P14416 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
DRD3 P35462 1/20 0.39
HIF1A Q16665 1/20 0.39
HSD17B10 Q99714 1/20 0.39
DRD4 P21917 1/20 0.39
HTR2C P28335 6/20 0.38
HTR2A P28223 5/20 0.38
HTR2B P41595 5/20 0.38
ALDH1A1 P00352 1/20 0.33
HTT P42858 1/20 0.33
ADCY5 O95622 1/20 0.31
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7146392 0.80 PARP1 (0.38) ARMAOADRD2KDM4ECYP2C9
SCHEMBL30512035 0.77 DRD2 (0.32) MAOADRD2KDM4ECYP2C9TSHR
SCHEMBL24130901 0.77 AR (0.42) ARHTR2CHTR2AHTR2BALDH1A1
SCHEMBL15678430 0.77 DRD2 (0.32) MAOADRD2KDM4ECYP2C9TSHR
SCHEMBL2259340 0.75 AR (0.44) ARHTR2CHTR2AHTR2B
SCHEMBL2631582 0.69 CA1 (0.49) ARKDM4EHSD17B10HTR2CALDH1A1
SCHEMBL21707867 0.69 CA1 (0.49) ARKDM4EHSD17B10HTR2CALDH1A1
SCHEMBL13894872 0.68 HTR2C (0.51) ARHTR2CHTR2AHTR2B
SCHEMBL3875241 0.68 HTR2C (0.53) ARKDM4EHSD17B10HTR2CHTR2A
SCHEMBL31158608 0.68 HTR2C (0.49) ARHTR2CHTR2AHTR2BKDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103517703-B Stain and application thereof 天野酶制品株式会社 2016-11-09 CN claimed
EP-2623093-B1 DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES AMANO ENZYME INC (JP) 2016-05-25 EP claimed
US-20140359950-A1 DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE AMANO ENZYME INC. (JP) 2014-12-11 US claimed
EP-2708223-B1 DYEING AGENT AND USE FOR SAME AMANO ENZYME INC (JP) 2017-02-01 EP disclosed
EP-3067041-A1 METHOD FOR DYEING KERATIN FIBERS, KERATIN FIBER DYE Shisei Chemical Co., Ltd. (JP) 2016-09-14 EP disclosed
US-9358198-B2 Dyeing of keratin fibers using indole analogue AMANO ENZYME INC. (JP) 2016-06-07 US disclosed
EP-2623093-B1 DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES AMANO ENZYME INC (JP) 2016-05-25 EP disclosed
US-20140359950-A1 DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE AMANO ENZYME INC. (JP) 2014-12-11 US disclosed
US-8740994-B2 Dyeing agent and use for same AMANO ENZYME INC. (JP) 2014-06-03 US disclosed
EP-2708223-A1 DYEING AGENT AND USE FOR SAME Amano Enzyme Inc. (JP) 2014-03-19 EP disclosed
US-20140068875-A1 DYEING AGENT AND USE FOR SAME AMANO ENZYME INC (JP) 2014-03-13 US disclosed
EP-1602718-A1 NEUTRAL PHENOL OXIDASE Mandom Corporation (JP) 2005-12-07 EP disclosed
US-6958080-B2 Compositions for dyeing keratinous fiber LION CORPORATION (JP) 2005-10-25 US disclosed
US-20050170485-A1 Culture having phenol oxidase-like activity MANDOM CORPORATION (JP) 2005-08-04 US disclosed
EP-1533371-A1 CULTURE HAVING PHENOL OXIDASE-LIKE ACTIVITY Mandom Corporation (JP) 2005-05-25 EP disclosed
US-20030106166-A1 Compositions for dyeing keratinous fiber LION CORPORATION (JP) 2003-06-12 US disclosed
EP-1254650-A2 Hair dye composition Kao Corporation (JP) 2002-11-06 EP disclosed
EP-1234569-A1 COMPOSITIONS FOR DYEING HORNY FIBERS Lion Corporation (JP) 2002-08-28 EP disclosed
EP-1189576-A2 HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN Lion Corporation (JP) 2002-03-27 EP disclosed
WO-2001000144-A2 HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN LION CORPORATION (JP) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030106166-A1 Compositions for dyeing keratinous fiber KRT18, LPO, CKMT1A; CKMT1B AR 3430/4885MAOA 58/4885DRD2 4691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.