Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14139768 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL4805222 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL4805210 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL20985448 | 0.96 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL26637906 | 0.96 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL6265861 | 0.94 | MEN1 (0.61) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL12349212 | 0.93 | MEN1 (0.66) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL16694460 | 0.93 | MEN1 (0.66) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL17199807 | 0.93 | MEN1 (0.64) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL28927797 | 0.91 | MEN1 (0.61) | ALDH1A1MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162794-B1 | ALKYL SUBSTITUTED AZETIDINES AS CATIONIC LIPID | KYOWA KIRIN CO LTD (JP) | 2020-09-16 | — | — | EP | disclosed |
| US-20170224619-A1 | CATIONIC LIPID | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2017-08-10 | — | — | US | disclosed |
| EP-3162794-A1 | CATIONIC LIPID | Kyowa Hakko Kirin Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170224619-A1 | CATIONIC LIPID | NPC1L1, NPC1, SGMS1 | ALDH1A1 3134/4885CNR1 719/4885CNR2 1192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.