Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14139768 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL4805222 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL18784334 | 1.00 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL20985448 | 0.96 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL26637906 | 0.96 | ALDH1A1 (0.58) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL6265861 | 0.94 | MEN1 (0.61) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL12349212 | 0.93 | MEN1 (0.66) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL16694460 | 0.93 | MEN1 (0.66) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL17199807 | 0.93 | MEN1 (0.64) | ALDH1A1CNR1CNR2MEN1THRB | |
| SCHEMBL28927797 | 0.91 | MEN1 (0.61) | ALDH1A1MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43632-E1 | 1,3-propane diol esters and ethers and methods for their use in drug delivery | SCARISTA, LTD. (GB) | 2012-09-04 | — | — | US | disclosed |
| US-RE40546-E1 | 1,3-Propane diol esters and ethers and methods for their use in drug delivery | SCARISTA, LTD. (GB) | 2008-10-21 | — | — | US | disclosed |
| US-RE40480-E1 | 1,3-Propane diol esters and ethers and methods for their use in drug delivery | SCARISTA LIMITED (GB) | 2008-09-02 | — | — | US | disclosed |
| EP-0823897-B1 | NICOTINIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCARISTA LTD (GB) | 2004-07-28 | — | — | EP | disclosed |
| US-6555700-B1 | Bioactives (drugs, nutrients) in a form in which they are lipophilic so that they can pass lipid barriers (membranes, skin etc.) in the body readily; glycerides of esterified, aminated or etherified bioactives; side effect reduction | SCOTIA HOLDINGS PLC (GB) | 2003-04-29 | — | — | US | disclosed |
| EP-0823889-B1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCARISTA LTD (GB) | 2002-09-18 | — | — | EP | disclosed |
| US-6015821-A | SKIN, PSYCHOLOGICAL AND CARDIOVASCULAR DISORDERS; ANTICARCINOGENIC, ANTIINFLAMMATORY AND ANTIDIABETIC AGENTS | SCARISTA LIMITED (IM) | 2000-01-18 | — | — | US | disclosed |
| EP-0823897-A1 | NICOTINIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCOTIA HOLDINGS PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| EP-0823889-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1998-02-18 | — | — | EP | disclosed |
| WO-1996034846-A1 | 1,3-PROPANE DIOL DERIVATIVES AS BIOACTIVE COMPOUNDS | SCOTIA HOLDINGS PLC (GB) | 1996-11-07 | — | — | WO | disclosed |
| WO-1996034858-A1 | NICOTINIC ACID ESTERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCOTIA HOLDINGS PLC (GB) | 1996-11-07 | — | — | WO | disclosed |