Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18583489 | 1.00 | TRPM8 (0.50) | TRPM8EPHX1TLR2TLR1TRPV1 | |
| SCHEMBL18563058 | 0.86 | TRPM8 (0.52) | TRPM8EPHX1TLR2TLR1TRPV1 | |
| SCHEMBL18547621 | 0.83 | TRPM8 (0.53) | TRPM8EPHX1TRPV1 | |
| SCHEMBL18547556 | 0.82 | TRPM8 (0.61) | TRPM8EPHX1TRPV1 | |
| SCHEMBL18583870 | 0.82 | TRPM8 (0.61) | TRPM8EPHX1TRPV1 | |
| SCHEMBL18583642 | 0.81 | TRPM8 (0.50) | TRPM8EPHX1TRPV1 | |
| SCHEMBL14197475 | 0.80 | TRPM8 (0.51) | TRPM8EPHX1TRPV1 | |
| SCHEMBL18583635 | 0.79 | CYP3A4 (0.41) | TRPM8TLR2TLR1TRPV1MEN1 | |
| SCHEMBL18583440 | 0.78 | EPHX1 (0.54) | TRPM8EPHX1TRPV1ALDH1A1 | |
| SCHEMBL18786188 | 0.78 | TRPM8 (0.55) | TRPM8EPHX1TRPV1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070418-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |