Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18563058 | 0.80 | TRPM8 (0.52) | TRPM8EPHX1TRPV1GAAMEN1 | |
| SCHEMBL2857549 | 0.80 | TRPM8 (0.54) | TRPM8EPHX1TRPV1TRPA1 | |
| SCHEMBL2058006 | 0.80 | TRPM8 (0.54) | TRPM8EPHX1TRPV1TRPA1 | |
| SCHEMBL4379359 | 0.80 | EPHX1 (0.58) | TRPM8EPHX1TRPV1TRPA1 | |
| SCHEMBL18786181 | 0.78 | TRPM8 (0.50) | TRPM8EPHX1TRPV1MEN1KMT2A | |
| SCHEMBL18583489 | 0.78 | TRPM8 (0.50) | TRPM8EPHX1TRPV1MEN1KMT2A | |
| SCHEMBL15016269 | 0.77 | EPHX1 (0.58) | TRPM8EPHX1TRPV1TRPA1 | |
| SCHEMBL3228965 | 0.77 | EPHX1 (0.58) | TRPM8EPHX1TRPV1TRPA1 | |
| SCHEMBL930592 | 0.77 | EPHX1 (0.58) | TRPM8EPHX1TRPV1TRPA1 | |
| SCHEMBL29177116 | 0.77 | EPHX1 (0.58) | TRPM8EPHX1TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017070418-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |