SCHEMBL18786338

SCHEMBL18786338

OC(c1ccccc1)(c1ccccc1)c1cc(Cl)ccc1-c1cc2ccccc2c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
HPGD P15428 1/20 0.41
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP19A1 P11511 5/20 0.39
ACSS2 Q9NR19 1/20 0.37
CFTR P13569 1/20 0.37
GOPC Q9HD26 1/20 0.37
GPR84 Q9NQS5 1/20 0.36
CYP3A4 P08684 3/20 0.36
CYP3A5 P20815 3/20 0.36
GRM2 Q14416 2/20 0.35
TRPM4 Q8TD43 1/20 0.35
CYP11B1 P15538 1/20 0.35
GUSB P08236 1/20 0.35
KDM4E B2RXH2 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20127198 0.87 CYP3A4 (0.43) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL10331289 0.83 HSD17B10 (0.46) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL18786339 0.83 CYP1A2 (0.33) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL29549155 0.83 MEN1 (0.41) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL18786342 0.83 CYP1A2 (0.41) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL18770229 0.82 TRPM4 (0.37) HPGDHIF1AHSD17B10GPR84GRM2
SCHEMBL19003783 0.81 CYP1A2 (0.39) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL18787176 0.81 ACSS2 (0.30) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL16219725 0.80 CYP19A1 (0.39) CYP1A2CYP2D6CYP2C9HPGDCYP2C19
SCHEMBL24743383 0.77 CYP2A6 (0.44) CYP1A2CYP2D6CYP2C9HPGDCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017069443-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 2017-04-27 WO disclosed