SCHEMBL19003783

SCHEMBL19003783

Cc1cc(-c2cc3ccccc3c3ccccc23)c(C(O)(c2ccccc2)c2ccccc2)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.39
HPGD P15428 3/20 0.39
HSD17B10 Q99714 3/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
HIF1A Q16665 2/20 0.39
CYP2C9 P11712 1/20 0.39
CFTR P13569 1/20 0.35
GOPC Q9HD26 1/20 0.35
CYP19A1 P11511 3/20 0.34
CYP11B1 P15538 1/20 0.33
TRPM4 Q8TD43 1/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP2A6 P11509 1/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18786342 0.81 CYP1A2 (0.41) CYP1A2HPGDHSD17B10CYP2D6CYP2C19
SCHEMBL18786338 0.81 CYP1A2 (0.41) CYP1A2HPGDHSD17B10CYP2D6CYP2C19
SCHEMBL10331289 0.78 HSD17B10 (0.46) CYP1A2HPGDHSD17B10CYP2D6CYP2C19
SCHEMBL20127198 0.77 CYP3A4 (0.43) CYP1A2HPGDHSD17B10CYP2D6CYP2C19
SCHEMBL29549155 0.75 MEN1 (0.41) CYP1A2HPGDHSD17B10CYP2D6CYP2C19
SCHEMBL17841053 0.68 TRPM4 (0.42) CYP1A2HPGDHSD17B10CYP2D6CYP2C19
SCHEMBL18770229 0.66 TRPM4 (0.37) HPGDHSD17B10HIF1ACYP11B1TRPM4
SCHEMBL29637136 0.66 ALDH1A1 (0.60) CYP1A2HPGDHSD17B10HIF1ACYP11B1
SCHEMBL7905250 0.66 ALDH1A1 (0.60) CYP1A2HPGDHSD17B10HIF1ACYP11B1
SCHEMBL20414478 0.65 TRPM4 (0.42) CYP1A2HPGDHSD17B10HIF1ACYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017104767-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME TDK株式会社 2017-06-22 WO disclosed