Methionine

Methionine

SCHEMBL187874

CSCC[C@H](N)C(=O)O.N=[SH2]=O

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 10/20 0.49
BHMT2 Q9H2M3 1/20 0.49
RNPEP Q9H4A4 1/20 0.47
NOS2 P35228 3/20 0.45
NOS3 P29474 2/20 0.45
NOS1 P29475 2/20 0.45
PMP22 Q01453 2/20 0.44
GRM8 O00222 1/20 0.42
GRM6 O15303 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GSR P00390 1/20 0.42
CYP1A2 P05177 1/20 0.42
GRIK1 P39086 1/20 0.42
GRM5 P41594 1/20 0.42
GRIA1 P42261 1/20 0.42
GRIA2 P42262 1/20 0.42
GRIA3 P42263 1/20 0.42
SLC1A3 P43003 1/20 0.42
SLC1A2 P43004 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL187871 1.00 BHMT (0.49) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL4258427 0.93 BHMT (0.46) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL4258424 0.93 BHMT (0.46) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL8402808 0.92 BHMT (0.52) BHMTBHMT2RNPEPNOS2NOS3
Methionine SCHEMBL11582567 0.92 BHMT (0.42) BHMTBHMT2RNPEPNOS2NOS3
Glutamine SCHEMBL831563 0.90 PMP22 (0.59) BHMTBHMT2RNPEPNOS2NOS3
Glutamine SCHEMBL831561 0.90 PMP22 (0.59) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL23361954 0.90 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL8983115 0.90 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL287590 0.90 BHMT (0.57) BHMTBHMT2RNPEPNOS2NOS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5045 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4747275-A1 VECTORS INCORPORATING A COMBINATION OF PROMOTERS DRIVING SELECTABLE MARKER EXPRESSION Amgen Inc. (US) 2026-05-27 EP claimed
US-12570536-B2 Ammonia synthesis methods and systems PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-03-10 US claimed
EP-4655404-A1 GLUTAMINE SYNTHETASE MARKER FOR RECOMBINANT EXPRESSION Shanghai Zhenge Biotechnology Co., Ltd. (CN) 2025-12-03 EP claimed
US-20250332141-A1 A PHARMACEUTICAL COMPOSITION COMPRISING AN INHIBITOR OF GLUTAMINE SYNTHETASE ENZYME TO COMBAT ARTEMISININ RESISTANCE IN MALARIA INSTITUTE OF LIFE SCIENCES (IN) 2025-10-30 US claimed
WO-2025202830-A1 METHOD FOR ENHANCING PRODUCTIVITY OF CLONES EXPRESSING PEMBROLIZUMAB INTAS PHARMACEUTICALS LTD. (IN) 2025-10-02 WO claimed
US-20250129127-A1 Systems for Amplification of AAV Rep and Cap Proteins SHAPE THERAPEUTICS INC. 2025-04-24 US claimed
US-20250115666-A1 CELL CULTURE METHODS FOR PRODUCING THERAPEUTIC PROTEINS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-04-10 US claimed
US-20250101402-A1 SELECTABLE MARKERS FOR EUKARYOTIC EXPRESSION SYSTEM SHANGHAI ZHENGE BIOTECHNOLOGY CO., LTD. (CN) 2025-03-27 US claimed
US-20250066491-A1 NOVEL MARKERS FOR RECOMBINANT PRODUCTION SYSTEM SHANGHAI ZHENGE BIOTECHNOLOGY CO., LTD. (CN) 2025-02-27 US claimed
US-5757408-A PRINTING IMAGE ON SUBSTRATE COATED WITH AMINO-ACID DERIVATIVE ADDITIVE; QUICK DRYING OF INK, OPTICAL DENSITY, NONCURLING XEROX CORPORATION (US) 1998-05-26 US claimed
EP-0824919-A2 Therapeutic methods and compositions for use therein Holt, John Alfred Gorton (AU) 1998-02-25 EP claimed
US-5683793-A Ink jet transparencies XEROX CORPORATION (US) 1997-11-04 US claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
US-5545819-A TRANSFORMED CELLS AND PLANTS NOT ONLY TOLERATE GLUTAMINE SYNTHETASE INHIBITORS BUT ARE EFFECTIVELY STIIMULATED BY SUCH HERBICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-13 US claimed
EP-0531031-B1 Compositions for use in cancer therapy HOLT JOHN ALFRED GORTON (AU) 1995-11-02 EP claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
EP-0531031-A1 Compositions for use in cancer therapy Holt, John Alfred Gorton (AU) 1993-03-10 EP claimed
US-4659670-A Biological desulfurization of coal THE STANDARD OIL COMPANY 1987-04-21 US claimed
EP-0126443-A2 A process for the selective preparation of microorganisms capable of reproducible reduction of sulfur and use of the microorganism for microbial desulfurization of coal THE STANDARD OIL COMPANY (US) 1984-11-28 EP claimed