Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 10/20 | 0.57 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.57 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.56 |
| ▸ | NOS2 | P35228 | 3/20 | 0.52 |
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.50 |
| ▸ | GRM6 | O15303 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GSR | P00390 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.50 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Racemethionine SCHEMBL16062299 | 1.00 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL162030 | 1.00 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL5584463 | 1.00 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL9504290 | 1.00 | — | — | |
| Racemethionine SCHEMBL5617580 | 1.00 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL8983115 | 1.00 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Racemethionine SCHEMBL23361954 | 1.00 | BHMT (0.57) | BHMTBHMT2RNPEPNOS2NOS3 | |
| Methionine SCHEMBL4226 | 1.00 | — | — | |
| Racemethionine SCHEMBL126688 | 1.00 | — | — | |
| Racemethionine SCHEMBL31367634 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2449488-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES Life Sciences AG (AT) | 2012-05-09 | — | — | EP | disclosed |
| EP-2427773-A1 | METHOD OF DIAGNOSING ASPHYXIA | Keller, Matthias (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-8034166-B2 | Carbon dioxide absorbent requiring less regeneration energy | BASF SE (DE) | 2011-10-11 | — | — | US | disclosed |
| US-20110064828-A1 | TREATMENT OF METASTATIC TUMORS AND OTHER CONDITIONS | Novelos Therapeutics, Incorporated (US) | 2011-03-17 | — | — | US | disclosed |
| WO-2011000753-A1 | METHOD FOR NORMALIZATION IN METABOLOMICS ANALYSIS METHODS WITH ENDOGENOUS REFERENCE METABOLITES | BIOCRATES LIFE SCIENCES AG (AT) | 2011-01-06 | — | — | WO | disclosed |
| WO-2010128054-A1 | METHOD OF DIAGNOSING ASPHYXIA | BIOCRATES LIFE SCIENCES AG (AT) | 2010-11-11 | — | — | WO | disclosed |
| US-20060270013-A1 | Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways | METABOLIC EXPLORER (FR) | 2006-11-30 | — | — | US | disclosed |
| WO-2006042915-A1 | FOODS AND METHODS FOR IMPROVING ANIMAL GROWTH | ADISSEO IRELAND LIMITED (IE) | 2006-04-27 | — | — | WO | disclosed |
| US-6777209-B1 | DNA SEQUENCES ENCODING FOR RIBONUCLEOTIDE REDUCTASE AND THIOREDOXIN FURTHER COMPRISE DNA SEQUENCES ENCODING FOR THYMIDYLATE SYNTHASE AND/OR TRANSCRIPTION UNITS COMPRISING SEQUENCES ENCODING FOR URIDINE KINASE | SMITHKLINE BEECHAM CORPORATION | 2004-08-17 | — | — | US | disclosed |
| EP-1015479-A4 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | LILLY CO ELI (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-1015479-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 2000-07-05 | — | — | EP | disclosed |
| WO-1998046631-A1 | COMBINATORIAL LIBRARIES OF PEPTIDOMIMETIC MACROCYCLES AND PROCESSES THEREFOR | ELI LILLY AND COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110064828-A1 | TREATMENT OF METASTATIC TUMORS AND OTHER CONDITIONS | PDIA5, GSTK1, GSTM2 | BHMT 2933/4885BHMT2 3022/4885RNPEP 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.