SCHEMBL1878772

SCHEMBL1878772

COC(=O)CNC1C=CC=CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.33
TET2 Q6N021 1/20 0.32
RECQL P46063 1/20 0.32
TSHR P16473 2/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28047710 0.98 EPHX2 (0.32) EPHX2TET2RECQLTSHR
SCHEMBL4591586 0.94 CA12 (0.32)
SCHEMBL1888270 0.85 GAA (0.38) EPHX2
SCHEMBL607551 0.80
SCHEMBL10798431 0.80
SCHEMBL27817578 0.79
Hydrochloric Acid SCHEMBL5031179 0.79
SCHEMBL10529046 0.79 KDM1A (0.36)
SCHEMBL27791582 0.79
SCHEMBL28043248 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118834859-A For synthesizing cefradine penicillin G acylase of (A) 上海邦林生物科技有限公司 2024-10-25 CN claimed
CN-113387824-A High-purity D-dihydro phenyl glycine methyl ester and preparation method thereof 华北制药股份有限公司 2021-09-14 CN claimed
EP-1641933-B1 PROCESS FOR THE PREPARATION OF CEPHRADINE DSM SINOCHEM PHARM NL BV (NL) 2017-12-20 EP claimed
EP-1931619-B1 METHANESULPHONIC ACID SALT OF DIHYDROPHENYLGLYCINE METHYL ESTER OR OF PHENYLGLYCINE METHYL ESTER DSM SINOCHEM PHARM NL BV (NL) 2015-06-24 EP claimed
US-20110104748-A1 PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) 2011-05-05 US claimed
EP-2121960-A1 PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS DSM IP Assets B.V. (NL) 2009-11-25 EP claimed
WO-2008110527-A1 PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS DSM IP ASSETS B.V. (NL) 2008-09-18 WO claimed
CN-118834859-A For synthesizing cefradine penicillin G acylase of (A) 上海邦林生物科技有限公司 2024-10-25 CN disclosed
CN-109971743-B Penicillin G acylase mutant derived from achromobacter CCM4824 and application thereof 艾美科健株式会社 2022-09-06 CN disclosed
CN-113387824-A High-purity D-dihydro phenyl glycine methyl ester and preparation method thereof 华北制药股份有限公司 2021-09-14 CN disclosed
CN-109971743-A From the penicillin G acylase mutant of achromobacter CCM4824 and its application 艾美科健株式会社 2019-07-05 CN disclosed
CN-109971742-A From the penicillin G acylase mutant of achromobacter CCM 4824 and its application 艾美科健株式会社 2019-07-05 CN disclosed
US-20180222848-A1 Salt of Dihydrophenylglycine Methyl Ester DSM SINOCHEM PHARM NL BV (NL) 2018-08-09 US disclosed
WO-2008110527-A1 PROCESS FOR THE PREPARATION OF BETA-LACTAM COMPOUNDS DSM IP ASSETS B.V. (NL) 2008-09-18 WO disclosed
WO-2008110529-A1 PROCESS FOR THE PREPARATION OF AMINO ACID METHYL ESTERS DSM IP ASSETS B.V. (NL) 2008-09-18 WO disclosed
EP-1931619-A2 PROCESS FOR ESTERIFICATION OF AN ORGANIC ACID DSMIP Assets B.V. (NL) 2008-06-18 EP disclosed
WO-2007039522-A2 PROCESS FOR ESTERIFICATION OF AN ORGANIC ACID DSM IP ASSETS B.V. (NL) 2007-04-12 WO disclosed
US-20060189802-A1 Process for the preparation of cephradine DSM SINOCHEM PHARMACEUTICALS NETHERLANDS B.V. (NL) 2006-08-24 US disclosed
EP-1641933-A2 PROCESS FOR THE PREPARATION OF CEPHRADINE DSM IP Assets B.V. (NL) 2006-04-05 EP disclosed
WO-2005003367-A2 PROCESS FOR THE PREPARATION OF CEPHRADINE DSM IP ASSETS B.V. (NL) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180222848-A1 Salt of Dihydrophenylglycine Methyl Ester DNPEP, DDC, DHPS EPHX2 1897/4885TET2 113/4885RECQL 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.