Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1886391 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL15271188 | 0.98 | — | — | |
| Fluoride Ion SCHEMBL1131005 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL1888191 | 0.83 | CYP11B2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL1886613 | 0.81 | CYP11B2 (0.36) | — | |
| Bromide SCHEMBL16424548 | 0.79 | — | — | |
| Fluoride Ion SCHEMBL1130924 | 0.79 | — | — | |
| Bromide SCHEMBL16424594 | 0.78 | CYP11B2 (0.32) | — | |
| Fluoride Ion SCHEMBL16424022 | 0.78 | CYP11B2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL6067517 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9394388-B2 | Hybrid supported metallocene catalyst, method for preparing the same, and process for preparing polyolefin using the same | SK INNOVATION CO., LTD. (KR) | 2016-07-19 | — | — | US | claimed |
| US-20150025204-A1 | Hybrid Supported Metallocene Catalyst, Method for Preparing the Same, and Process for Preparing Polyolefin Using the Same | SK INNOVATION CO., LTD. (KR) | 2015-01-22 | — | — | US | claimed |
| WO-2013133595-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYOLEFIN USING THE SAME | SK INNOVATION CO., LTD. (KR) | 2013-09-12 | — | — | WO | claimed |
| US-9394388-B2 | Hybrid supported metallocene catalyst, method for preparing the same, and process for preparing polyolefin using the same | SK INNOVATION CO., LTD. (KR) | 2016-07-19 | — | — | US | disclosed |
| US-20150025204-A1 | Hybrid Supported Metallocene Catalyst, Method for Preparing the Same, and Process for Preparing Polyolefin Using the Same | SK INNOVATION CO., LTD. (KR) | 2015-01-22 | — | — | US | disclosed |
| WO-2013133595-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, METHOD FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYOLEFIN USING THE SAME | SK INNOVATION CO., LTD. (KR) | 2013-09-12 | — | — | WO | disclosed |
| US-8399375-B2 | Supported metallocene catalyst composition and a process for the preparation of polyolefin using the same | SK GLOBAL CHEMICAL CO., LTD. (KR) | 2013-03-19 | — | — | US | disclosed |
| US-20110105705-A1 | Metallocene Supported Catalyst Composition and a Process for the Preparation of Polyolefin Using the Same | SK ENERGY CO., LTD. (KR) | 2011-05-05 | — | — | US | disclosed |
| EP-2258731-A2 | METALLOCENE SUPPORTED CATALYST COMPOSITION AND A PROCESS FOR THE PREPARATION OF POLYOLEFIN USING THE SAME | SK Energy Co., Ltd. (KR) | 2010-12-08 | — | — | EP | disclosed |
| EP-1294565-B1 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2010-03-17 | — | — | EP | disclosed |
| EP-1373404-B1 | POLYETHYLENE BLENDS | UNIVATION TECH LLC (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1325073-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | ExxonMobil Chemical Patents Inc. (US) | 2003-07-09 | — | — | EP | disclosed |
| WO-2003033585-A1 | POLYMERIC MEMBRANE COMPOSITIONS | EXXONMOBILE CHEMICAL PATENTS INC. (US) | 2003-04-24 | — | — | WO | disclosed |
| EP-1299470-A1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | ExxonMobil Chemical Patents Inc. (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1294565-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | ExxonMobil Chemical Patents Inc. (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2003000790-A1 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES OR LINEAR LOWDENSITY POLYETHYLENES AS IMPACT MODIFIERS | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2003-01-03 | — | — | WO | disclosed |
| WO-2002000436-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENE AND LOW DENSITY POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2002-01-03 | — | — | WO | disclosed |
| WO-2001098409-A1 | VERY LOW DENSITY POLYETHYLENE AND HIGH DENSITY POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001098406-A2 | POLYETHYLENE BLENDS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| WO-2001098372-A2 | METALLOCENE-PRODUCED VERY LOW DENSITY POLYETHYLENES | EXXONMOBIL CHEMICAL PATENTS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |