Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25820125 | 0.77 | ALOX15 (0.41) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL22053555 | 0.72 | ALOX15 (0.39) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL18789479 | 0.72 | ALOX15 (0.39) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL12896580 | 0.72 | ALOX15 (0.39) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL26022514 | 0.72 | ALOX15 (0.41) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL22892113 | 0.70 | ALOX15 (0.41) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL19538327 | 0.70 | ALOX15 (0.41) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL18788952 | 0.69 | ALDH1A1 (0.33) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL18788964 | 0.69 | ALDH1A1 (0.33) | ALOX15ALDH1A1LMNATHRBMAPK1 | |
| SCHEMBL25819971 | 0.68 | ALOX15 (0.39) | ALOX15ALDH1A1LMNATHRBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10526563-B2 | Mixtures having (4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexamethyl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole)(Ambrocenide®) | SYMRISE AG (DE) | 2020-01-07 | — | — | US | disclosed |
| US-20170114299-A1 | New mixtures having (4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexamethyl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole)(Ambrocenide®) | SYMRISE AG (DE) | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10526563-B2 | Mixtures having (4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexamethyl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole)(Ambrocenide®) | OR51E2, OR10J3, TAS2R7 | ALOX15 1444/4885ALDH1A1 395/4885LMNA 3905/4885 |
| US-20170114299-A1 | New mixtures having (4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexamethyl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole)(Ambrocenide®) | OR51E2, OR10J3, TAS2R7 | ALOX15 1463/4885ALDH1A1 378/4885LMNA 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.