Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13832798 | 1.00 | FKBP1A (0.58) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL15626755 | 1.00 | FKBP1A (0.58) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL26694862 | 0.90 | POLB (0.53) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL1881008 | 0.90 | FKBP1A (0.61) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL2274911 | 0.88 | POLB (0.61) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL2274909 | 0.88 | POLB (0.61) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL11026079 | 0.88 | FKBP1A (0.56) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL21340465 | 0.86 | FKBP1A (0.55) | FKBP1APOLBMMEL1MEN1KMT2A | |
| SCHEMBL19361276 | 0.85 | FKBP1A (0.54) | FKBP1APOLBMMEL1LTA4H | |
| SCHEMBL5733042 | 0.85 | FKBP1A (0.54) | FKBP1APOLBMMEL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939513-B2 | Tetracycline derivatives as antibacterial agents | DR. REDDY'S LABORATORIES LIMITED (IN) | 2011-05-10 | — | — | US | disclosed |
| WO-2009073056-A1 | NOVEL TETRACYCLINE DERIVATIVES AS ANTIBACTERIAL AGENTS | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-06-11 | — | — | WO | disclosed |
| US-20090111776-A1 | Novel tetracycline derivatives as antibacterial agents | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111776-A1 | Novel tetracycline derivatives as antibacterial agents | TREH, TEAD1, TET1 | FKBP1A 851/4885POLB 2619/4885MMEL1 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.