Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790857 | 0.98 | KMO (0.45) | KMOASIC3PIM1CYP11B2CTSS | |
| SCHEMBL18790607 | 0.92 | KMO (0.40) | KMOASIC3PIM1CTSSCTSK | |
| SCHEMBL18790599 | 0.88 | DHODH (0.48) | ASIC3PIM1CYP11B2USP30DHODH | |
| SCHEMBL18790856 | 0.87 | DHODH (0.46) | ASIC3PIM1USP30DHODHADORA1 | |
| SCHEMBL18729702 | 0.86 | ASIC3 (0.49) | KMOASIC3PIM1CYP11B2USP30 | |
| SCHEMBL18790589 | 0.86 | ASIC3 (0.41) | ASIC3PIM1CTSSCTSKUSP30 | |
| SCHEMBL22134616 | 0.85 | KMO (0.44) | KMOASIC3CYP11B2CTSSCTSK | |
| SCHEMBL18790498 | 0.85 | ASIC3 (0.40) | ASIC3PIM1CTSSCTSKUSP30 | |
| SCHEMBL18643803 | 0.84 | S1PR1 (0.44) | KMOCYP11B2CTSSCTSKADORA1 | |
| SCHEMBL18790535 | 0.83 | ASIC3 (0.39) | ASIC3PIM1CTSSCTSKUSP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159350-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | Universal Display Corporation (US) | 2017-04-26 | — | — | EP | disclosed |