SCHEMBL18790752

SCHEMBL18790752

C=CCc1cccc2c1C(=O)NS2(=O)=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RET P07949 2/20 0.53
GRK5 P34947 2/20 0.53
TYRO3 Q06418 2/20 0.53
DYRK1B Q9Y463 2/20 0.53
CA12 O43570 12/20 0.42
CA9 Q16790 12/20 0.42
CA2 P00918 11/20 0.42
CA1 P00915 8/20 0.42
CA4 P22748 7/20 0.42
CA7 P43166 7/20 0.42
KDM4E B2RXH2 2/20 0.42
LMNA P02545 2/20 0.42
USP2 O75604 1/20 0.42
BCHE P06276 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
KMT2A Q03164 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
GABRA1 P14867 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18790753 0.85 RET (0.50) RETGRK5TYRO3DYRK1BCA12
SCHEMBL7280743 0.80 RET (0.59) RETGRK5TYRO3DYRK1BCA12
SCHEMBL7280710 0.76 RET (0.54) RETGRK5TYRO3DYRK1BCA12
SCHEMBL7281293 0.76 RET (0.57) RETGRK5TYRO3DYRK1BCA12
SCHEMBL82972 0.75 GABRA1 (0.45) RETGRK5TYRO3DYRK1BCA12
SCHEMBL20646900 0.75 RET (0.53) RETGRK5TYRO3DYRK1BCA12
SCHEMBL18790754 0.74 RET (0.51) RETGRK5TYRO3DYRK1BCA12
Saccharin SCHEMBL27788845 0.73 CA12 (0.51) CA12CA9CA2CA1CA4
SCHEMBL18790756 0.72 RET (0.49) RETGRK5TYRO3DYRK1BCA12
SCHEMBL5824091 0.71 GABRA1 (0.58) KDM4ELMNAKMT2AGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10290900-B2 Non-aqueous electrolytic solution and lithium ion secondary battery comprising same NIPPON SHOKUBAI CO., LTD. (JP) 2019-05-14 US disclosed
US-20170117582-A1 NON-AQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM ION SECONDARY BATTERY COMPRISING SAME NIPPON SHOKUBAI CO., LTD. (JP) 2017-04-27 US disclosed