SCHEMBL82972

SCHEMBL82972

C=CCc1cccc2c1S(=O)(=O)NC2=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.45
GABRB2 P47870 1/20 0.45
LMNA P02545 3/20 0.42
KDM4E B2RXH2 3/20 0.42
CA12 O43570 3/20 0.42
CA9 Q16790 3/20 0.42
CA2 P00918 2/20 0.42
USP2 O75604 1/20 0.42
CA1 P00915 1/20 0.42
BCHE P06276 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
KMT2A Q03164 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
GAA P10253 2/20 0.36
HTT P42858 2/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13440433 0.79 CA12 (0.46) LMNAKDM4ECA12CA9CA2
SCHEMBL8369191 0.76 CA12 (0.39) LMNAKDM4ECA12CA9CA2
SCHEMBL529430 0.76 CA12 (0.43) LMNAKDM4ECA12CA9CA2
SCHEMBL1661224 0.76 CA12 (0.46) LMNAKDM4ECA12CA9CA2
SCHEMBL3807234 0.75 CA12 (0.46) LMNAKDM4ECA12CA9CA2
SCHEMBL18790752 0.75 RET (0.53) GABRA1GABRB2LMNAKDM4ECA12
SCHEMBL19666184 0.75 CA12 (0.34) LMNAKDM4ECA12CA9CA2
SCHEMBL3806455 0.74 PTGER4 (0.47) LMNAKDM4ECA12CA9CA2
SCHEMBL18762952 0.73 GABRA1 (0.46) GABRA1GABRB2LMNAKDM4ECA12
SCHEMBL230481 0.73 CA9 (0.50) LMNAKDM4ECA12CA9CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1980 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240230660-A1 PROTEIN MELT ANALYSIS USING DIPYRROMETHENEBORON DIFLUORIDE COMPOUNDS LIFE TECHNOLOGIES CORP (US) 2024-07-11 US claimed
US-11883392-B2 Pharmaceutical composition for nasal delivery OREXO AB (SE) 2024-01-30 US claimed
WO-2023249087-A1 PHARMACEUTICAL COMPOSITION AND METHOD FOR PRODUCING SAME 三生医薬株式会社 2023-12-28 WO claimed
CN-114401775-B Isolation of color body carotenoids from fruits 卡利亚里大学 2023-11-07 CN claimed
CN-115836225-A Detection of elements using sugar-lectin coupling 伊鲁米纳公司 2023-03-21 CN claimed
EP-3996687-A1 PHARMACEUTICAL COMPOSITION FOR NASAL DELIVERY Orexo AB (SE) 2022-05-18 EP claimed
CN-114401775-A Isolation of chromoplast carotenoids from fruit 卡利亚里大学 2022-04-26 CN claimed
CN-108342258-B Liquid detergent composition 花王株式会社 2022-04-01 CN claimed
US-20210401825-A1 PHARMACEUTICAL COMPOSITION FOR NASAL DELIVERY OREXO AB (SE) 2021-12-30 US claimed
WO-2021050687-A1 STABLE AQUEOUS FORMULATIONS OF AFLIBERCEPT Coherus Biosciences, Inc. (US) 2021-03-18 WO claimed
US-5372744-A Shampoos; low irritant to skin and hair KAO CORPORATION (JP) 1994-12-13 US claimed
EP-0538762-A1 Hair cosmetic KAO CORPORATION (JP) 1993-04-28 EP claimed
US-5057311-A Mixture of alkyl saccharide surfactant and cationic polymer KAO CORPORATION (JP) 1991-10-15 US claimed
EP-0444778-A1 Use of alkyl saccharides to enhance the penetration of drugs ALCON LABORATORIES, INC. (US) 1991-09-04 EP claimed
US-5015414-A Polyoxyethylene modified saccharide blend with amphoteric surfactant KAO CORPORATION (JP) 1991-05-14 US claimed
EP-0422508-A2 Liquid detergent composition KAO CORPORATION (JP) 1991-04-17 EP claimed
EP-0409005-A2 Detergent composition KAO CORPORATION (JP) 1991-01-23 EP claimed
EP-0358216-A2 Low-irritant detergent composition Kao Corporation (JP) 1990-03-14 EP claimed
US-4483979-A Polar solvent extraction of colored materials from alkylsaccharides under essentially anhydrous conditions THE PROCTER & GAMBLE COMPANY (US) 1984-11-20 US claimed
US-4227911-A PLANT GROWTH STIMULANTS AND ANTIFOULING AGENTS FOR SPRAYING DEVICES CONKLIN COMPANY, INC. (US) 1980-10-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240230660-A1 PROTEIN MELT ANALYSIS USING DIPYRROMETHENEBORON DIFLUORIDE COMPOUNDS PFDN6, S100A6, MB GABRA1 2962/4885GABRB2 3620/4885LMNA 1943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.