Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 2/20 | 0.48 |
| ▸ | SKP1 | P63208 | 2/20 | 0.48 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17207658 | 0.84 | GPR119 (0.43) | CKS1BSKP1SKP2GPR119DDB1 | |
| SCHEMBL18502868 | 0.80 | DDB1 (0.53) | CKS1BSKP1SKP2GPR119DDB1 | |
| SCHEMBL3272696 | 0.76 | CKS1B (0.69) | CKS1BSKP1SKP2GPR119MAP4K4 | |
| SCHEMBL23560770 | 0.74 | CKS1B (0.57) | CKS1BSKP1SKP2GPR119DDB1 | |
| SCHEMBL14523390 | 0.74 | CKS1B (0.54) | CKS1BSKP1SKP2GPR119MAP4K4 | |
| SCHEMBL1432444 | 0.73 | CKS1B (0.56) | CKS1BSKP1SKP2GPR119MAP4K4 | |
| SCHEMBL1432688 | 0.73 | CKS1B (0.56) | CKS1BSKP1SKP2GPR119MAP4K4 | |
| SCHEMBL26124274 | 0.73 | GPR119 (0.54) | CKS1BSKP1SKP2GPR119MAP4K4 | |
| SCHEMBL30546217 | 0.73 | GPR119 (0.54) | CKS1BSKP1SKP2GPR119MAP4K4 | |
| SCHEMBL3268897 | 0.73 | CKS1B (0.48) | CKS1BSKP1SKP2GPR119MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381904-B1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2021-07-28 | — | — | EP | disclosed |
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2020-07-21 | — | — | US | disclosed |
| WO-2017069226-A1 | NOVEL NITROGEN-CONTAINING AROMATIC HETEROCYCLIC COMPOUND | 田辺三菱製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10717731-B2 | Nitrogen-containing aromatic heterocyclic compound | REN, NR3C2, NR5A1 | CKS1B 840/4885SKP1 1872/4885SKP2 4479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.