SCHEMBL1879216

SCHEMBL1879216

CCCOC(=O)C=COC

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.61
ATM Q13315 1/20 0.54
ALOX5 P09917 1/20 0.46
APP P05067 4/20 0.44
TSHR P16473 2/20 0.41
HPGD P15428 1/20 0.41
MAPT P10636 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.34
KEAP1 Q14145 1/20 0.33
NFE2L2 Q16236 1/20 0.33
ESR1 P03372 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
KDR P35968 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1879214 1.00 HCAR2 (0.61) HCAR2ATMALOX5APPTSHR
SCHEMBL1574088 0.88 ATM (0.73) HCAR2ATMAPPTSHRHPGD
SCHEMBL136328 0.88 ATM (0.73) HCAR2ATMAPPTSHRHPGD
SCHEMBL448454 0.84 HCAR2 (0.82) HCAR2ATMALOX5APPTSHR
SCHEMBL448456 0.84 HCAR2 (0.82) HCAR2ATMALOX5APPTSHR
SCHEMBL322228 0.84 HCAR2 (0.82) HCAR2ATMALOX5APPTSHR
Acetic Acid SCHEMBL28083170 0.83 ATM (0.66) HCAR2ATMAPPTSHRHPGD
SCHEMBL23203149 0.83 HCAR2 (0.61) HCAR2ATMALOX5APPTSHR
SCHEMBL1986279 0.83 TSHR (0.50) HCAR2ATMALOX5TSHRHPGD
SCHEMBL1880342 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023132572-A1 RADIATIVE COOLING METAMATERIAL COMPOSITION AND METAMATERIAL FILM PREPARED FROM SAME 한양대학교 산학협력단 2023-07-13 WO disclosed
EP-3805313-B1 ACRYLIC ELASTOMER COMPOSITION DENKA COMPANY LTD (JP) 2023-05-03 EP disclosed
EP-3805313-A1 ACRYLIC ELASTOMER COMPOSITION Denka Company Limited (JP) 2021-04-14 EP disclosed
US-9873781-B2 Acrylic rubber composition, acrylic rubber molded product, and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2018-01-23 US disclosed
CN-103635527-B Acrylate copolymer that heat-staple polyamide is filled and preparation method thereof 纳幕尔杜邦公司 2016-11-16 CN disclosed
CN-103732682-B For the method preparing the acrylate polymer that heat-stabilised poly amide is filled 纳幕尔杜邦公司 2016-11-09 CN disclosed
EP-2803700-B1 ACRYLIC RUBBER COMPOSITION, ACRYLIC RUBBER MOLDED PRODUCT, AND METHOD FOR PRODUCING SAME DAIKIN IND LTD (JP) 2016-07-20 EP disclosed
CN-104870181-A Laminates of fluoroelastomer and heat-resistant acrylate elastomer DU PONT 2015-08-26 CN disclosed
US-20140346707-A1 ACRYLIC RUBBER COMPOSITION, ACRYLIC RUBBER MOLDED PRODUCT, AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2014-11-27 US disclosed
EP-2803700-A1 ACRYLIC RUBBER COMPOSITION, ACRYLIC RUBBER MOLDED PRODUCT, AND METHOD FOR PRODUCING SAME Daikin Industries, Ltd. (JP) 2014-11-19 EP disclosed
WO-1999044100-A1 CURABLE COMPOSITIONS COATES BROTHERS PLC (GB) 1999-09-02 WO disclosed
EP-0811659-A2 Acrylic rubber composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1997-12-10 EP disclosed
EP-0525710-B1 Fibers of graft copolymers having a propylene polymer material backbone MONTELL NORTH AMERICA INC (US) 1997-10-29 EP disclosed
EP-0522233-B1 Impact resistant graft copolymers HIMONT INC (US) 1995-06-07 EP disclosed
US-5349016-A Modulus, flexibility, elongation; carpets HIMONT INCORPORATED (US) 1994-09-20 US disclosed
EP-0525710-A1 Fibers of graft copolymers having a propylene polymer material backbone MONTELL NORTH AMERICA INC. (US) 1993-02-03 EP disclosed
EP-0522233-A1 Impact resistant graft copolymers Himont Incorporated (US) 1993-01-13 EP disclosed
CN-1064685-A IMPACT RESISTANT GRAFT COPOLYMERS HIMONT INC (US) 1992-09-23 CN disclosed
EP-0342812-A2 Photopolymerisable compositions suitable for recording holographic information IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-11-23 EP disclosed
US-4156034-A COPOLYMER OF ACRYLIC ESTER AND STYRENE DERIVATIVE AS COATING AGENT HITACHI, LTD. (JP) 1979-05-22 US disclosed