SCHEMBL1879308

SCHEMBL1879308

Oc1cc(Br)cc(O)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.56
CYP3A4 P08684 1/20 0.56
TSHR P16473 1/20 0.56
GABRA1 P14867 2/20 0.48
GABRB1 P18505 2/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
SELL P14151 2/20 0.47
SELP P16109 2/20 0.47
SELE P16581 1/20 0.47
PTPN1 P18031 3/20 0.43
ALOX15 P16050 3/20 0.41
ALDH1A1 P00352 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
LMNA P02545 2/20 0.41
HPGD P15428 2/20 0.41
CA6 P23280 2/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69509 0.84 CYP3A4 (0.72) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL2050124 0.82 CYP3A4 (0.46) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL12189844 0.80 CYP3A4 (0.43) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL16599884 0.80 TSHR (0.43) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL7520723 0.79 CYP3A4 (0.47) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL25012039 0.76 CYP3A4 (0.45) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL6541836 0.76 ERN1 (0.60) CYP3A4ALOX15ALDH1A1CA1CA2
SCHEMBL8285504 0.74 AKR1C3 (0.69) TDP1CYP3A4TSHRSELLSELP
SCHEMBL6542408 0.74 PTPN1 (0.41) TDP1CYP3A4TSHRGABRA1GABRB1
SCHEMBL16595415 0.74 CYP3A4 (0.39) TDP1CYP3A4TSHRGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262615-A1 ANTIOXIDANTS CONTAINING DIAZIRINE FUNCTIONALITIES, COMPOSITIONS COMPRISING THEM AND USE THEREOF BELLARE ANUJ (US) 2025-12-26 WO claimed
CN-119708346-A Polymer, preparation method thereof, retarder and oil well cement paste 中国石油天然气集团有限公司 2025-03-28 CN claimed
CN-114351440-A Nano composite antibacterial non-woven fabric and preparation process and application thereof 广东宝创环保新材料制品有限公司 2022-04-15 CN claimed
WO-2025262615-A1 ANTIOXIDANTS CONTAINING DIAZIRINE FUNCTIONALITIES, COMPOSITIONS COMPRISING THEM AND USE THEREOF BELLARE ANUJ (US) 2025-12-26 WO disclosed
EP-4621028-A1 FLUORESCENCE RECOVERY IN NANOGRAPHENE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2025-09-24 EP disclosed
CN-120082284-A UV skin-feel coating for nursing products, preparation method and application thereof 金桥德克新材料股份有限公司 2025-06-03 CN disclosed
CN-115745885-B Chiral liquid crystal fluorescent material and application thereof 常州大学 2025-05-02 CN disclosed
WO-2025066105-A1 POLYMER, PREPARATION METHOD THEREFOR, RETARDER, AND OIL WELL CEMENT SLURRY 中国石油天然气集团有限公司 2025-04-03 WO disclosed
CN-119708346-A Polymer, preparation method thereof, retarder and oil well cement paste 中国石油天然气集团有限公司 2025-03-28 CN disclosed
CN-113330096-B Use of substituted or unsubstituted polycyclic aromatic compounds for high resolution microscopy 马克斯·普朗克索赔科学公司 2024-05-31 CN disclosed
CN-114409679-B Target membrane small molecule and preparation method and application thereof 南京邮电大学 2024-01-16 CN disclosed
US-6831093-B2 For selectively modulating the activation, repression, agonism and antagonism effects of the glucocorticoid receptor in a patient; for therapy and prophylaxis of obesity, diabetes, depression, neurodegeneration or an inflammatory disease THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-12-14 US disclosed
EP-1467730-A1 NON-STEROIDAL LIGANDS FOR THE GLUCOCORTICOID RECEPTOR, COMPOSITIONS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2004-10-20 EP disclosed
US-20040072681-A1 Solid catalyst component for olefin polymerization and catalyst TOHO TITANIUM CO., LTD. (JP) 2004-04-15 US disclosed
US-20030176478-A1 Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof NIH-DEITR 2003-09-18 US disclosed
WO-2003061651-A1 NON-STEROIDAL LIGANDS FOR THE GLUCOCORTICOID RECEPTOR, COMPOSITIONS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-07-31 WO disclosed
EP-1260524-A1 SOLID CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST Toho Titanium Co., Ltd. (JP) 2002-11-27 EP disclosed
US-5087548-A POSITIVE TYPE RADIATION-SENSITIVE RESIN COMPOSITION JAPAN SYNTHETIC RUBBER CO., INC. (JP) 1992-02-11 US disclosed
EP-0227487-A2 Positive type radiation-sensitive resin composition JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1987-07-01 EP disclosed
US-3987109-A POLYMERIZATION OF POLYFUNCTIONAL PHENOLS UNIVERSAL OIL PRODUCTS COMPANY (US) 1976-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176478-A1 Non-steroidal ligands for the glucocorticoid receptor, compositions and uses thereof NR3C1, NR3C2, GCGR TDP1 4121/4885CYP3A4 2531/4885TSHR 297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.