SCHEMBL2050124

SCHEMBL2050124

Oc1cc(Br)cc(F)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
GABRA1 P14867 2/20 0.40
GABRB1 P18505 2/20 0.40
GABRA2 P47869 1/20 0.40
GABRB2 P47870 1/20 0.40
AKR1B1 P15121 1/20 0.38
PTPN1 P18031 2/20 0.37
ALOX15 P16050 2/20 0.35
ALOX12 P18054 1/20 0.35
DGAT1 O75907 1/20 0.35
CA3 P07451 1/20 0.35
CA6 P23280 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
CA5B Q9Y2D0 1/20 0.35
ERCC1 P07992 1/20 0.34
ERCC4 Q92889 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13029 0.88 CYP3A4 (0.50) CYP3A4TSHRTDP1GABRA1GABRB1
Lithium SCHEMBL31361451 0.86 CYP3A4 (0.48) CYP3A4TSHRTDP1GABRA1GABRB1
Potassium SCHEMBL31361438 0.86 CYP3A4 (0.48) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL31361467 0.86 CYP3A4 (0.48) CYP3A4TSHRTDP1GABRA1GABRB1
Bromide SCHEMBL4668136 0.86 CYP3A4 (0.48) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL1879308 0.82 TDP1 (0.56) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL189947 0.81 CYP3A4 (0.38) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL11744136 0.81 CYP3A4 (0.65) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL29375214 0.81 CYP3A4 (0.38) CYP3A4TSHRTDP1GABRA1GABRB1
SCHEMBL15174010 0.77 CA9 (0.41) CYP3A4TSHRTDP1GABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125378-A2 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2026-05-07 US disclosed
EP-4721737-A1 USE OF PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND HAVING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE FOR TREATING ANEMIA-RELATED DISEASES Scinnohub Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP disclosed
EP-4658650-A1 HETEROCYCLIC COMPOUNDS Beone Medicines I GmbH (CH) 2025-12-10 EP disclosed
US-20250353846-A1 Heterocyclic Compounds BEONE MEDICINES I GMBH (CH) 2025-11-20 US disclosed
US-20250346593-A1 IMIDAZO(1,2-1)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS INTERLINE THERAPEUTICS INC (US) 2025-11-13 US disclosed
US-12441703-B2 Carboxamides as modulators of sodium channels VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-10-14 US disclosed
US-20250179032-A1 HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE HORIZON THERAPEUTICS IRELAND DAC (IE) 2025-06-05 US disclosed
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE SCINNOHUB PHARMACEUTICAL CO., LTD. (CN) 2025-05-08 US disclosed
CN-119768400-A Fused ring compound, application thereof and pharmaceutical composition containing fused ring compound 苏州信诺维医药科技股份有限公司 2025-04-04 CN disclosed
CN-119698416-A Imidazo (1, 2-A) pyridine derivatives as RIPK2 inhibitors 英特莱治疗公司 2025-03-25 CN disclosed
US-7956222-B2 Methods for producing dibromofluorobenzene derivatives EISAI R&D MANAGEMENT CO., LTD (JP) 2011-06-07 US disclosed
US-7956222-B2 Methods for producing dibromofluorobenzene derivatives EISAI R&D MANAGEMENT CO., LTD (JP) 2011-06-07 US disclosed
US-7807068-B2 reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays MERCK PATENT GESELLSCHAFT (DE) 2010-10-05 US disclosed
US-7807068-B2 reacting 4-halo-2,6-difluorophenol with protecting group, dehalogenating to form protected phenol ether group, reacting with boronic acid/ester, coupling in presence of catalyst, deblocking, etherifying, esterifying; for optical, electro-optical and electronic use, liquid-crystal media and displays MERCK PATENT GESELLSCHAFT (DE) 2010-10-05 US disclosed
US-20090141215-A1 POLYMERIZABLE COMPOUNDS MERCK PATENT GESELLSCHAFT (DE) 2009-06-04 US disclosed
US-20090141215-A1 POLYMERIZABLE COMPOUNDS MERCK PATENT GESELLSCHAFT (DE) 2009-06-04 US disclosed
US-20080045753-A1 Methods For Producing Dibromofluorobenzene Derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-02-21 US disclosed
US-20080045753-A1 Methods For Producing Dibromofluorobenzene Derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-02-21 US disclosed
US-20080045753-A1 Methods For Producing Dibromofluorobenzene Derivatives EISAI R&D MANAGEMENT CO., LTD. (JP) 2008-02-21 US disclosed
EP-1780192-A1 METHOD FOR PRODUCING DIBROMOFLUOROBENZENE DERIVATIVE Eisai R&D Management Co., Ltd. (JP) 2007-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125378-A2 Heterocyclic Compounds NFATC1, CD4, MALT1 CYP3A4 284/4885TSHR 362/4885TDP1 1626/4885
US-20250145635-A1 COMPOUND CONTAINING BIS(AZANYLYLIDENE) SULFONYL STRUCTURE AND USE THEREOF IN MEDICINE BCL9, USP9X, BCL9L CYP3A4 4126/4885TSHR 2326/4885TDP1 3466/4885
US-20250179032-A1 HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE SLC2A9, SLC2A1, SLC2A8 CYP3A4 3056/4885TSHR 3179/4885TDP1 2394/4885
US-20250353846-A1 Heterocyclic Compounds NFATC1, CD4, ACIN1 CYP3A4 2289/4885TSHR 3470/4885TDP1 2259/4885
US-12441703-B2 Carboxamides as modulators of sodium channels TRPV1, SCN2A, SCN10A CYP3A4 2128/4885TSHR 3163/4885TDP1 3674/4885
US-20250346593-A1 IMIDAZO(1,2-1)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS RIPK2, RIPK1, RIPK4 CYP3A4 2868/4885TSHR 2854/4885TDP1 938/4885
US-20090141215-A1 POLYMERIZABLE COMPOUNDS VCL, LCP1, LPXN CYP3A4 3971/4885TSHR 4880/4885TDP1 3198/4885
US-20080045753-A1 Methods For Producing Dibromofluorobenzene Derivatives CYP2F1, BLVRB, CBR1 CYP3A4 148/4885TSHR 1979/4885TDP1 2258/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.