SCHEMBL187934

SCHEMBL187934

O=P(O)(O)OC[C@H]1O[C@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.81

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.81
AMDHD2 Q9Y303 1/20 0.64
IGF2R P11717 4/20 0.55
UMPS P11172 4/20 0.44
P2RY14 Q15391 2/20 0.43
ATIC P31939 1/20 0.43
DNPH1 O43598 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30471819 1.00 FBP1 (0.81) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL708955 1.00 FBP1 (0.81) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL5001024 1.00 FBP1 (0.81) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL16710620 1.00 FBP1 (0.81) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL4997000 1.00 FBP1 (0.81) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL24450790 1.00 FBP1 (0.81) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL4308485 1.00 FBP1 (0.81) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL14016411 0.98 FBP1 (0.78) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL21926734 0.98 FBP1 (0.78) FBP1AMDHD2IGF2RUMPSP2RY14
SCHEMBL22107998 0.98 FBP1 (0.78) FBP1AMDHD2IGF2RUMPSP2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122075713-A Deaminase and use of transaminase in the treatment of polyglutamine diseases 2026-05-26 CN claimed
EP-3874056-B1 ENZYMATIC METHOD FOR PREPARATION OF UDP-GLCNAC MAX PLANCK GESELLSCHAFT (DE) 2023-06-14 EP claimed
EP-2235201-B1 METHODS AND COMPOSITIONS FOR ASSAYING HOMOCYSTEINE GEN ATOMICS (US) 2012-10-31 EP claimed
EP-4747382-A1 COMPOSITIONS AND METHODS FOR MANAGEMENT OF WHITEFLY Natural Resources Institute (GB) 2026-05-27 EP disclosed
CN-122075713-A Deaminase and use of transaminase in the treatment of polyglutamine diseases 2026-05-26 CN disclosed
WO-2025019548-A9 COMPOSITIONS AND METHODS FOR MANAGEMENT OF WHITEFLY NATIONAL RESOURCES INSTITUTE (GB) 2025-04-17 WO disclosed
US-20250027105-A1 COMPOSITIONS AND METHODS FOR MANAGEMENT OF WHITEFLY NATIONAL AGRICULTURAL RESEARCH ORGANIZATION (UG) 2025-01-23 US disclosed
WO-2025019548-A1 COMPOSITIONS AND METHODS FOR MANAGEMENT OF WHITEFLY NATIONAL RESOURCES INSTITUTE (GB) 2025-01-23 WO disclosed
US-20240350027-A1 Methods and Apparatus for Benchtop Metabolite Profiling in Situ VIBO HEALTH INC (US) 2024-10-24 US disclosed
US-20230414571-A1 APPLICATION OF SMALL-MOLECULE COMPOUND IN PREPARATION OF ANTITUMOR DRUG SOOCHOW UNIVERSITY (CN) 2023-12-28 US disclosed
US-11834690-B2 Microorganisms and methods for the biosynthesis of adipate, hexamethylenediamine and 6-aminocaproic acid GENOMATICA, INC. (US) 2023-12-05 US disclosed
EP-2061899-B1 BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME METABOLON INC (US) 2012-08-29 EP disclosed
US-20120185226-A1 MAMMALIAN CELL LINE MODELS AND RELATED METHODS GENOMATICA, INC. (US) 2012-07-19 US disclosed
EP-2401696-A1 MAMMALIAN CELL LINE MODELS AND RELATED METHODS GT Life Sciences, Inc. (US) 2012-01-04 EP disclosed
US-20100292331-A1 Biomarkers for Prostate Cancer and Methods Using the Same METABALON, INC. (US) 2010-11-18 US disclosed
US-20100291605-A1 ASSAYS FOR S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-11-18 US disclosed
WO-2010098865-A1 MAMMALIAN CELL LINE MODELS AND RELATED METHODS GT LIFE SCIENCES, INC. (US) 2010-09-02 WO disclosed
US-20090259451-A1 REVERSE ENGINEERING GENOME-SCALE METABOLIC NETWORK RECONSTRUCTIONS FOR ORGANISMS WITH INCOMPLETE GENOME ANNOTATION AND DEVELOPING CONSTRAINTS USING PROTON FLUX STATES AND NUMERICALLY-DETERMINED SUB-SYSTEMS UNIVERSITY OF DELAWARE (US) 2009-10-15 US disclosed
US-20070298998-A1 Biomarkers for amyotrophic lateral sclerosis and methods using the same METABOLON, INC. (US) 2007-12-27 US disclosed
WO-2007087541-A2 ASSAYS FOR S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2007-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230414571-A1 APPLICATION OF SMALL-MOLECULE COMPOUND IN PREPARATION OF ANTITUMOR DRUG ABCG2, SLC43A1, SLC7A5 FBP1 2516/4885AMDHD2 1697/4885IGF2R 918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.