SCHEMBL187940

SCHEMBL187940

COc1ccc(-c2nnn[nH]2)cc1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
KDM4E B2RXH2 7/20 0.54
HSD17B10 Q99714 1/20 0.54
GAA P10253 1/20 0.51
MPI P34949 1/20 0.51
GFER P55789 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
TDP1 Q9NUW8 1/20 0.51
PDE4A P27815 3/20 0.46
PDE4B Q07343 2/20 0.46
PDE4C Q08493 2/20 0.46
PDE4D Q08499 2/20 0.46
ALOX5 P09917 1/20 0.46
EPHX2 P34913 1/20 0.46
HPGD P15428 3/20 0.45
MAPK1 P28482 2/20 0.45
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6608296 0.87 GRK6 (0.45) ALDH1A1KDM4EHSD17B10GAAMPI
SCHEMBL6789801 0.87 DHFR (0.44) ALDH1A1KDM4EHSD17B10GAAMPI
SCHEMBL1250505 0.85 NOX1 (0.49) GAAGFERALOX5MAPT
SCHEMBL10765716 0.85 KDM4E (0.40) ALDH1A1KDM4EHSD17B10GAAMPI
SCHEMBL705661 0.85 MAPT (0.49) ALDH1A1KDM4EHSD17B10GAAMPI
SCHEMBL3044550 0.85 HSD17B10 (0.47) ALDH1A1KDM4EHSD17B10GAATDP1
SCHEMBL8258446 0.85 PDE4A (0.48) ALDH1A1KDM4EHSD17B10GAAMPI
SCHEMBL12970703 0.82 MKNK1 (0.52) ALDH1A1KDM4EHSD17B10GAAMEN1
SCHEMBL12892200 0.82 MPO (0.57) ALDH1A1GAAMEN1KMT2ASMN1; SMN2
SCHEMBL8848806 0.82 KDM4E (0.42) ALDH1A1KDM4EHSD17B10GAAMPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646402-A Method for detecting and enumerating microorganisms 3M创新有限公司 2021-11-12 CN claimed
EP-2200562-B1 DENTAL COMPOSITION FOR DETECTING BACTERIA, KIT OF PARTS AND USE THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2014-04-23 EP claimed
EP-1294922-B1 TREATING CANCER USING ORGANELLE CRYSTALLIZING AGENTS KONG QINGZHONG (CN) 2010-04-14 EP claimed
US-7524872-B2 Method and composition for treating cancer using cellular organelle crystallizing agents KONG QINGZHONG 2009-04-28 US claimed
US-20080166753-A1 Microbial Growth Assay UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2008-07-10 US claimed
US-20060286170-A1 Method and composition for treating cancer using cellular organelle crystallizing agents KONG QINGZHONG 2006-12-21 US claimed
US-7102011-B2 Methods and compositions for the visualization of cellular organelles using tetrazolium salts KONG QINGZHONG 2006-09-05 US claimed
WO-2005098023-A1 MICROBIAL GROWTH ASSAY UNIVERSITY TECHNOLOGIES INTERNATIONAL INC. (CA) 2005-10-20 WO claimed
US-6864272-B2 Method and composition for treating cancer using cellular organelle crystallizing agents KONG QINGZHONG (US) 2005-03-08 US claimed
US-6703216-B2 AN OXIDIZED COFACTOR FOR THE FIRST OXIDOREDUCTASE THAT IS REDUCED UPON OXIDATION OF GHB BY THE FIRST OXIDOREDUCTASE IS IN TURN OXIDIZED BY ANOTHER OXIDOREDUCTASE CAUSING DETECTABLE CONVERSION OF CHROMOGEN OR DYE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-03-09 US claimed
US-20020086345-A1 Methods and compositions for the visualization of cellular organelles using tetrazolium salts KONG QINGZHONG (US) 2002-07-04 US claimed
US-6376525-B1 Tetrazolium salts and derivatives, preferably tetrazolium red and tetrazolium violet, in combination with chemotherapeutic agents delivered in a polylactic acid carrier; noninvasive antitumor treatments KONG QINGZHONG (US) 2002-04-23 US claimed
US-6368818-B1 VISUAL AIDS AND CANCER TREATMENT KONG QINGZHONG (US) 2002-04-09 US claimed
WO-2001082780-A2 METHOD FOR TREATING CANCER, VISUALIZING CELL STRUCTURES, AND ISOLATING ORGANELLES USING ORGANELLE CRYSTALLIZING AGENTS KONG QINGZHONG (US) 2001-11-08 WO claimed
EP-0971037-A2 Stable reagent for formazan-based assay Kirkegaard & Perry Laboratories, Inc. (US) 2000-01-12 EP claimed
EP-0620844-B1 CULTURE MEDIA DEVICE MINNESOTA MINING & MFG (US) 1996-01-03 EP claimed
EP-0620844-A1 CULTURE MEDIA DEVICE. MINNESOTA MINING & MFG (US) 1994-10-26 EP claimed
US-5232838-A CULTURE MEDIA DEVICE AND METHOD OF USE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-08-03 US claimed
WO-1993012218-A1 CULTURE MEDIA DEVICE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-24 WO claimed
US-4892817-A INDOXYL PHOSPHATE, TETRAZOLIUM SALT, AND WATER SOLUBLE FERRICYANIDE FERROCYANIDE SALT BIOGENEX LABORATORIES (US) 1990-01-09 US claimed