Lobenzarit

Lobenzarit

SCHEMBL187951

O=C(O)c1ccccc1Nc1cc(Cl)ccc1C(=O)O

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 10/20 0.63
AKR1C3 P42330 2/20 0.62
AKR1B10 O60218 1/20 0.62
AKR1B1 P15121 1/20 0.62
AKR1C4 P17516 1/20 0.62
AKR1C2 P52895 1/20 0.62
AKR1C1 Q04828 1/20 0.62
FTO Q9C0B1 2/20 0.60
PBRM1 Q86U86 1/20 0.59
FABP4 P15090 4/20 0.59
TTR P02766 2/20 0.58
MEN1 O00255 1/20 0.58
USP2 O75604 1/20 0.58
MT-CO2 P00403 1/20 0.58
LMNA P02545 1/20 0.58
PLA2G1B P04054 1/20 0.58
CYP1A2 P05177 1/20 0.58
PGR P06401 1/20 0.58
CYP3A4 P08684 1/20 0.58
HTR1A P08908 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lobenzarit SCHEMBL30753983 1.00 GRIK1 (0.63) GRIK1AKR1C3AKR1B10AKR1B1AKR1C4
Lobenzarit SCHEMBL1479150 0.98 GRIK1 (0.61) GRIK1AKR1C3AKR1B10AKR1B1AKR1C4
Lobenzarit SCHEMBL29453054 0.98 GRIK1 (0.61) GRIK1AKR1C3AKR1B10AKR1B1AKR1C4
Lobenzarit SCHEMBL9621335 0.98 GRIK1 (0.61) GRIK1AKR1C3AKR1B10AKR1B1AKR1C4
Lobenzarit SCHEMBL7935 0.98 GRIK1 (0.61) GRIK1AKR1C3AKR1B10AKR1B1AKR1C4
SCHEMBL6140792 0.92 FABP4 (0.62) GRIK1AKR1C3AKR1B10AKR1B1AKR1C4
SCHEMBL11603313 0.91 GRIK1 (0.62) GRIK1AKR1C3AKR1C2MEN1USP2
SCHEMBL14576292 0.90 GRIK1 (0.73) GRIK1AKR1C3FTOPBRM1FABP4
SCHEMBL30611313 0.90 GRIK1 (0.73) GRIK1AKR1C3FTOPBRM1FABP4
SCHEMBL16489012 0.90 EGFR (0.66) GRIK1AKR1C3AKR1B10AKR1C2AKR1C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1836 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250052736-A1 METHODS FOR DETERMINING A SOURCE OF WOOD PRODUCTS, WOOD PRESERVATIVE COMPOSITIONS, WOOD PRODUCTS, AND METHODS OF TREATING WOOD SUBSTRATES PNC BANK, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2025-02-13 US claimed
US-12157863-B2 Processing and gasification of construction and demolition materials Simonpietri Enterprises LLC (US) 2024-12-03 US claimed
US-12151133-B2 Timber remediation Treated Timber Remediation Pty. Ltd (AU) 2024-11-26 US claimed
US-20240084207-A1 PROCESSING AND GASIFICATION OF CONSTRUCTION AND DEMOLITION MATERIALS Simonpietri Enterprises LLC 2024-03-14 US claimed
US-20240017438-A1 SYSTEMS AND METHODS FOR WOOD POLE AND POST TREATMENT JEFFREY LOUIS D (US) 2024-01-18 US claimed
EP-3836905-B1 NOVEL ORAL COMPOSITION APILLET APS (DK) 2023-10-04 EP claimed
WO-2023077097-A1 PROCESSING AND GASIFICATION OF CONSTRUCTION AND DEMOLITION MATERIALS SIMONPIETRI MARIE JOELLE (US) 2023-05-04 WO claimed
US-20230132767-A1 PROCESSING AND GASIFICATION OF CONSTRUCTION AND DEMOLITION MATERIALS Simonpietri Enterprises LLC 2023-05-04 US claimed
US-20230047182-A1 A METHOD FOR IMPROVING DURABILITY AND WEATHERABILITY OF TIMBER BY ENGINEERING LAYERS ABODO WOOD LIMITED (NZ) 2023-02-16 US claimed
US-11554514-B2 Strong and tough structural wood materials, and methods for fabricating and use thereof UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2023-01-17 US claimed
EP-0759750-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO, Howard, K. (US) 1997-03-05 EP claimed
EP-0537313-B1 ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY GENTILI IST SPA (IT) 1996-01-17 EP claimed
WO-1995031194-A1 COMPOSITIONS FOR TREATMENT OF CHRONIC INFLAMMATORY DISEASES SHAPIRO HOWARD K (US) 1995-11-23 WO claimed
EP-0569411-B1 ACYLAMINO-ALKYLIDEN-HYDROXY-BISPHOSPHONIC ACIDS USEFUL IN THE THERAPY OF OSTEOARTICULAR DISEASES GENTILI IST SPA (IT) 1995-03-29 EP claimed
US-5330981-A Antiinflammatory agents ISTITUTO GENTILI S.P.A. (IT) 1994-07-19 US claimed
EP-0569411-A1 ACYLAMINO-ALKYLIDEN-HYDROXY-BISPHOSPHONIC ACIDS USEFUL IN THE THERAPY OF OSTEOARTICULAR DISEASES. GENTILI IST SPA (IT) 1993-11-18 EP claimed
EP-0537313-A1 ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY. GENTILI IST SPA (IT) 1993-04-21 EP claimed
WO-1992019584-A1 ARYLALKYL ESTERS OF 4,5-DIHYDROXY-9,10-DIHYDRO-9,10-DIOXO-2-ANTHRACENECARBOXYLIC ACID HAVING THERAPEUTICAL ACTIVITY ISTITUTO GENTILI S.P.A. (IT) 1992-11-12 WO claimed
WO-1992013864-A1 ACYLAMINO-ALKYLIDEN-HYDROXY-BISPHOSPHONIC ACIDS USEFUL IN THE THERAPY OF OSTEOARTICULAR DISEASES ISTITUTO GENTILI S.P.A. (IT) 1992-08-20 WO claimed
US-4092426-A LIVER DISORDERS CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1978-05-30 US claimed