Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.66 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.66 |
| ▸ | GRIK1 | P39086 | 6/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.61 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lobenzarit SCHEMBL187951 | 0.90 | GRIK1 (0.63) | GRIK1CYP2C9FTOPBRM1TTR | |
| Lobenzarit SCHEMBL30753983 | 0.90 | GRIK1 (0.63) | GRIK1CYP2C9FTOPBRM1TTR | |
| SCHEMBL6140792 | 0.89 | FABP4 (0.62) | GRIK1CYP2C9FTOPBRM1TTR | |
| Lobenzarit SCHEMBL7935 | 0.89 | GRIK1 (0.61) | GRIK1CYP2C9FTOPBRM1TTR | |
| Lobenzarit SCHEMBL1479150 | 0.89 | GRIK1 (0.61) | GRIK1CYP2C9FTOPBRM1TTR | |
| Lobenzarit SCHEMBL29453054 | 0.89 | GRIK1 (0.61) | GRIK1CYP2C9FTOPBRM1TTR | |
| Lobenzarit SCHEMBL9621335 | 0.89 | GRIK1 (0.61) | GRIK1CYP2C9FTOPBRM1TTR | |
| SCHEMBL24021599 | 0.87 | LMNA (0.62) | GRIK1CYP2C9FTOPBRM1TTR | |
| SCHEMBL14576292 | 0.87 | GRIK1 (0.73) | GRIK1CYP2C9CXCL8FTOPBRM1 | |
| SCHEMBL30611313 | 0.87 | GRIK1 (0.73) | GRIK1CYP2C9CXCL8FTOPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11173137-B2 | Compositions and methods to modulate chloride ion channel activity | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-11-16 | — | — | US | disclosed |
| US-20150051286-A1 | ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-19 | — | — | US | disclosed |
| US-20150051286-A1 | ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION | CHOUDHARY MUHAMMAD IQBAL (PK) | 2015-02-19 | — | — | US | disclosed |
| US-20150030539-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PIRAMAL IMAGING SA (CH) | 2015-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051286-A1 | ANTHRANILIC ACID DERIVATIVES: NOVEL INHIBITORS OF ADVANCED GLYCATION END-PRODUCTS (AGES) FORMATION | AGER, NFKBIA, DNPEP | EGFR 1218/4885ALK 1556/4885GRIK1 2669/4885 |
| US-20150030539-A1 | COMPOUNDS FOR USE IN IMAGING, DIAGNOSING AND/OR TREATMENT OF DISEASES OF THE CENTRAL NERVOUS SYSTEM OR OF TUMORS | PMP22, MEN1, VHL | EGFR 609/4885ALK 618/4885GRIK1 298/4885 |
| US-11173137-B2 | Compositions and methods to modulate chloride ion channel activity | CLCN2, CLIC1, CLIC4 | EGFR 4489/4885ALK 4528/4885GRIK1 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.