Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7296994 | 0.92 | HDAC6 (0.59) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL28860581 | 0.83 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC4MAPT | |
| SCHEMBL18795908 | 0.83 | HDAC4 (0.56) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL20550282 | 0.83 | HDAC6 (0.60) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL28659250 | 0.82 | NR1H4 (0.44) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL21175923 | 0.82 | HDAC4 (0.54) | HDAC6HDAC1HDAC8HDAC4NR1H4 | |
| SCHEMBL18796097 | 0.82 | HDAC4 (0.63) | HDAC6HDAC1HDAC8HDAC4 | |
| SCHEMBL18795910 | 0.82 | HDAC6 (0.51) | HDAC6HDAC1HDAC8NPC1RAB9A | |
| SCHEMBL22530783 | 0.81 | HDAC4 (0.53) | HDAC6HDAC1HDAC4 | |
| SCHEMBL20550192 | 0.81 | HDAC6 (0.49) | HDAC6HDAC1HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108347936-B | Microbicidal oxadiazole derivatives | 先正达参股股份有限公司 | 2021-04-20 | — | — | CN | disclosed |
| US-20180319753-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-11-08 | — | — | US | disclosed |
| EP-3367798-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072247-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-04 | — | — | WO | disclosed |
| WO-2017072247-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180319753-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | PRF1, NOX1, ARG1 | HDAC6 610/4885HDAC1 551/4885HDAC8 1766/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.