Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16795314 | 0.81 | ALDH1A1 (0.54) | KDM4EHPGDL3MBTL1TSHRPDE2A | |
| SCHEMBL18795956 | 0.75 | HTT (0.68) | HPGDL3MBTL1RXFP1CYP1A2CYP2C9 | |
| SCHEMBL18796404 | 0.74 | LCK (0.52) | KDM4EHPGDL3MBTL1TSHRNQO2 | |
| SCHEMBL18795929 | 0.73 | MAPT (0.50) | KDM4EHPGDL3MBTL1TSHRHTT | |
| SCHEMBL18796236 | 0.73 | NQO2 (0.44) | KDM4EHPGDL3MBTL1TSHRNQO2 | |
| SCHEMBL18292683 | 0.72 | HRH4 (0.46) | KDM4EHPGDL3MBTL1TSHRPDE2A | |
| SCHEMBL16695550 | 0.72 | S1PR4 (0.37) | KDM4ETSHRMAPTLMNANPC1 | |
| SCHEMBL24287258 | 0.71 | ALDH1A1 (0.50) | KDM4EHPGDL3MBTL1TSHRNQO2 | |
| SCHEMBL18796028 | 0.71 | SCD (0.43) | KDM4EHPGDL3MBTL1TSHRNQO2 | |
| SCHEMBL18795957 | 0.71 | NQO2 (0.50) | KDM4EL3MBTL1TSHRNQO2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368514-B1 | TRISUBSTITUTED SILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AG (DE) | 2021-08-18 | — | — | EP | disclosed |
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-06-16 | — | — | US | disclosed |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-01 | — | — | US | disclosed |
| EP-3368514-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | Bayer CropScience Aktiengesellschaft (DE) | 2018-09-05 | — | — | EP | disclosed |
| WO-2017072283-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10683311-B2 | Trisubstitutedsilylphenoxyheterocycles and analogues | PIK3C3, ERG28, DDT | KDM4E 508/4885HPGD 2875/4885L3MBTL1 2453/4885 |
| US-20190233444-A1 | TRISUBSTITUTEDSILYLPHENOXYHETEROCYCLES AND ANALOGUES | PIK3C3, ERG28, DDT | KDM4E 508/4885HPGD 2875/4885L3MBTL1 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.