Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15873735 | 0.84 | PSEN1 (0.30) | — | |
| SCHEMBL18796496 | 0.77 | — | — | |
| SCHEMBL21324013 | 0.77 | GRM5 (0.32) | HRH3 | |
| SCHEMBL18467311 | 0.70 | COMT (0.46) | HRH3 | |
| SCHEMBL20940198 | 0.68 | ACHE (0.35) | HRH3 | |
| SCHEMBL22017463 | 0.67 | ALDH1A1 (0.37) | HRH3 | |
| SCHEMBL24810210 | 0.67 | GRM5 (0.33) | — | |
| SCHEMBL20939379 | 0.67 | HRH3 (0.34) | HRH3 | |
| SCHEMBL23768705 | 0.67 | MAP3K5 (0.36) | — | |
| SCHEMBL14251268 | 0.62 | GRM5 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017072341-A1 | PYRIMIDONE DERIVATIVES AND THEIR USE IN THE TREATMENT, AMELIORATION OR PREVENTION OF A VIRAL DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2017-05-04 | — | — | WO | disclosed |