Dioxane

Dioxane

SCHEMBL1879738

C1COCCO1.CC(C)OC(C)C

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.43
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
PKM P14618 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxirane SCHEMBL17709710 0.96 TTR (0.36) TTR
Dioxane SCHEMBL4260711 0.88 TTR (0.33) TTR
Tetrahydrofuran SCHEMBL754746 0.87 ALDH1A1 (0.50)
SCHEMBL6829599 0.84 ALDH1A1 (0.47)
Tetrahydrofuran SCHEMBL6793997 0.82 ALDH1A1 (0.44) PKMSMN1; SMN2
Fluoride SCHEMBL27330547 0.80
SCHEMBL7240952 0.76
SCHEMBL1296 0.76
SCHEMBL10940023 0.76
SCHEMBL27912512 0.76 MAPK1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101709313-B Method for catalytic synthesizing beta-nitroalcohol compounds by using lipase in organic phase ZHEJIANG UNIVERSITY (CN) 2011-12-07 CN claimed
US-12014011-B2 Conductive film, sensor, touch panel, image display device, and conductive film with protection film DAI NIPPON PRINTING CO., LTD. (JP) 2024-06-18 US disclosed
US-20240123429-A1 COMPLEX OXIDE AND METHOD FOR PRODUCING THE SAME MITSUI MINING & SMELTING CO., LTD. (JP) 2024-04-18 US disclosed
US-20230418424-A1 SENSOR, GOODS, METHOD FOR MANUFACTURING SENSOR, AND CONDUCTOR DAI NIPPON PRINTING CO., LTD. (JP) 2023-12-28 US disclosed
EP-4292709-A1 COMPOSITE OXIDE AND METHOD FOR PRODUCING SAME Mitsui Mining & Smelting Co., Ltd. (JP) 2023-12-20 EP disclosed
CN-110612284-B Substituted indoline derivatives as dengue virus replication inhibitors 杨森制药公司 2023-10-31 CN disclosed
CN-116867740-A Composite oxide and method for producing same 三井金属矿业株式会社 2023-10-10 CN disclosed
US-11776710-B2 Electroconductive film, sensor, touch panel, and image display device DAI NIPPON PRINTING CO., LTD. (JP) 2023-10-03 US disclosed
CN-116745122-A Optical film and polarizing plate 住友化学株式会社 2023-09-12 CN disclosed
CN-116723938-A Optical film and polarizing plate 住友化学株式会社 2023-09-08 CN disclosed
EP-1092435-A1 REMEDIES FOR DIABETES KYOWA HAKKO KOGYO CO., LTD. (JP) 2001-04-18 EP disclosed
US-6008382-A REACTING PODOPHYLLOTOXIN WITH A PAIR OF REAGENTS CONSISTING OF METHANESULFONIC ACID, ON THE ONE HAND, AND DIMETHYL SULFIDE, D,L-METHIONINE, OR METHYLTHIOACETIC ACID, ON OTHER HAND IN PRESENCE OF WATER WITH OR WITHOUT SOLVENT PIERRE FABRE MEDICAMENT (FR) 1999-12-28 US disclosed
US-5356922-A Treatment of disturbances in microcirculation HOECHST AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
US-5232922-A Cardiovascular disorders HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-03 US disclosed
EP-0025354-A2 Method for making thiobiscarbamates UNION CARBIDE CORPORATION (US) 1981-03-18 EP disclosed
US-4179561-A REACTING A 3-DIAZOOXINDOLE WITH A SUBSTITUTED ACETYLENE E. R. SQUIBB & SONS, INC. (US) 1979-12-18 US disclosed
US-4112096-A ANTIALLERGENS E. R. SQUIBB & SONS, INC. (US) 1978-09-05 US disclosed
US-4105768-A Hypotensive substituted 1,2,4-triazoles ASTRA LAKEMEDEL AKTIEBOLAG (SE) 1978-08-08 US disclosed
US-4076818-A ANTIALLERGENS E. R. SQUIBB & SONS, INC. (US) 1978-02-28 US disclosed
US-4022905-A HYPOTENSIVE AGENTS ASTRA LAKEMEDEL AKTIEBOLAG (SW) 1977-05-10 US disclosed