Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6829599 | 0.97 | ALDH1A1 (0.47) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL6793997 | 0.94 | ALDH1A1 (0.44) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL9464982 | 0.87 | ALDH1A1 (0.38) | ALDH1A1 | |
| Dioxane SCHEMBL1879738 | 0.87 | TTR (0.43) | — | |
| Hexane SCHEMBL9503581 | 0.85 | LMNA (0.36) | ALDH1A1 | |
| Oxirane SCHEMBL17709710 | 0.83 | TTR (0.36) | — | |
| SCHEMBL1879739 | 0.81 | — | — | |
| Tetrahydrofuran SCHEMBL11521890 | 0.79 | — | — | |
| Dioxane SCHEMBL4260711 | 0.77 | TTR (0.33) | ALDH1A1 | |
| Tetrahydrofuran SCHEMBL28820736 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685566-A | Benzene arsenic oxide crystal form I, crystal form II and crystal form III and preparation method thereof | 江苏挪贝肽医药科技有限公司 | 2022-07-01 | — | — | CN | claimed |
| US-20240190815-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | SPRINGWORKS THERAPEUTICS, INC. | 2024-06-13 | — | — | US | disclosed |
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2024-06-06 | — | — | US | disclosed |
| US-11884610-B2 | Crystalline solids of mek inhibitor n-((r)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof | SPRINGWORKS THERAPEUTICS, INC. (US) | 2024-01-30 | — | — | US | disclosed |
| WO-2023161962-A1 | MURAMYL DIPEPTIDES AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-08-31 | — | — | WO | disclosed |
| US-20230032403-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | SpringWorks Therapeutics Inc. (US) | 2023-02-02 | — | — | US | disclosed |
| CN-114685566-A | Benzene arsenic oxide crystal form I, crystal form II and crystal form III and preparation method thereof | 江苏挪贝肽医药科技有限公司 | 2022-07-01 | — | — | CN | disclosed |
| US-11084780-B1 | Crystalline solids of MEK inhibitor N-((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof | SPRINGWORKS THERAPEUTICS, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| US-20200339565-A1 | PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2020-10-29 | — | — | US | disclosed |
| US-20190248785-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-4413011-A | Substituted 2,2-dimethyl-5-phenoxypentanoic acid benzamides as anti-arteriosclerotic agents and method | WARNER-LAMBERT COMPANY (US) | 1983-11-01 | — | — | US | disclosed |
| US-4397855-A | 4-(Substituted)-α, α-dimethyl-1-piperazine pentanoic acids and derivatives as anti-arteriosclerotic agents and method | WARNER-LAMBERT COMPANY (US) | 1983-08-09 | — | — | US | disclosed |
| US-4351950-A | Anti-arteriosclerotic agents | WARNER-LAMBERT COMPANY (US) | 1982-09-28 | — | — | US | disclosed |
| US-4340597-A | 1-Substituted-4-aryl-1,2,5,6-tetrahydro and hexahydropyridines | SCHERING CORPORATION (US) | 1982-07-20 | — | — | US | disclosed |
| EP-0032063-A2 | Novel substituted arylene compounds and processes for their production | WARNER-LAMBERT COMPANY (US) | 1981-07-15 | — | — | EP | disclosed |
| US-4145346-A | Preparation of 3β-hydroxy-27-norcholest-5-ene-25-one and intermediates thereof | MERCK & CO., INC. (US) | 1979-03-20 | — | — | US | disclosed |
| US-4105660-A | Preparation of 3β-hydroxy-27-norcholest-5,7-dien-25-one | MERCK & CO., INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4093807-A | Tricyclic β-lactams | SMITHKLINE CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4007189-A | VASODILATION, HYPOTENSIVE | SANKYO COMPANY LIMITED (JA) | 1977-02-08 | — | — | US | disclosed |
| US-3966765-A | Process for producing benzothiopyrans | WARNER-LAMBERT COMPANY (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182463-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ALDH1A1 1564/4885 |
| US-11084780-B1 | Crystalline solids of MEK inhibitor N-((R)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof | NRAS, BRAF, KSR2 | ALDH1A1 3616/4885 |
| US-20190248785-A1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | PREP, UNG, DPP4 | ALDH1A1 1564/4885 |
| US-11884610-B2 | Crystalline solids of mek inhibitor n-((r)-2,3-dihydroxypropoxy)-3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-benzamide and uses thereof | NRAS, BRAF, KSR2 | ALDH1A1 3605/4885 |
| US-20200339565-A1 | PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE | PREP, UNG, DPP4 | ALDH1A1 1478/4885 |
| US-20230032403-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | NRAS, BRAF, KSR2 | ALDH1A1 3360/4885 |
| US-20240190815-A1 | CRYSTALLINE SOLIDS OF MEK INHIBITOR N-((R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODO--PHENYLAMINO)-BENZAMIDE AND USES THEREOF | NRAS, BRAF, KSR2 | ALDH1A1 3466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.