Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Metolcarb. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metolcarb SCHEMBL118244 | 0.96 | LMNA (0.65) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL29413999 | 0.96 | LMNA (0.65) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL28786421 | 0.95 | LMNA (0.62) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL11681132 | 0.95 | LMNA (0.62) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL11000289 | 0.95 | LMNA (0.62) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL7079404 | 0.95 | LMNA (0.62) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL8024716 | 0.95 | LMNA (0.62) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL10450901 | 0.93 | LMNA (0.57) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL10632832 | 0.92 | LMNA (0.59) | LMNAALDH1A1FAAHCYP3A4MAPK1 | |
| Metolcarb SCHEMBL258226 | 0.92 | LMNA (0.59) | LMNAALDH1A1FAAHCYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016040427-A1 | CELLULOSE ESTER PLASTICS AND METHODS AND ARTICLES RELATING THERETO | CELANESE ACETATE LLC (US) | 2016-03-17 | — | — | WO | claimed |
| WO-2016040434-A1 | CELLULOSE ESTER PLASTICS AND METHODS AND ARTICLES RELATING THERETO | CELANESE ACETATE LLC (US) | 2016-03-17 | — | — | WO | claimed |
| US-20160068656-A1 | CELLULOSE ESTER PLASTICS AND METHODS AND ARTICLES RELATING THERETO | CELANESE ACETATE LLC (US) | 2016-03-10 | — | — | US | claimed |
| US-20160068665-A1 | CELLULOSE ESTER PLASTICS AND METHODS AND ARTICLES RELATING THERETO | CELANESE ACETATE LLC (US) | 2016-03-10 | — | — | US | claimed |
| US-5712362-A | Process for the production of UV-stable polycarbonates | BAYER AG (DE) | 1998-01-27 | — | — | US | claimed |
| US-5698665-A | Polycarbonate processes with supercritical carbon dioxide | XEROX CORPORATION (US) | 1997-12-16 | — | — | US | claimed |
| WO-1995025083-A1 | PROCESS FOR THE PREPARATION OF ARYL HALOFORMATES AND DIARYL CARBONATES | GALVAN, RAFAEL | 1995-09-21 | — | — | WO | claimed |
| US-5424473-A | Process for the preparation of aryl haloformates and diaryl carbonates | THE DOW CHEMICAL COMPANY (US) | 1995-06-13 | — | — | US | claimed |
| US-4414230-A | BLEND OF A POLYESTER-CARBONATE COPOLYMER AND A POLYESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-11-08 | — | — | US | claimed |
| US-4115206-A | Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing an organic carbonate | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-19 | — | — | US | claimed |
| JP-55098224-A | — | — | None | — | — | JP | disclosed |
| US-12390971-B2 | Process and system for blending a plasticizer with a polysaccharide ester polymer | CELANESE INTERNATIONAL CORPORATION (US) | 2025-08-19 | — | — | US | disclosed |
| EP-3527593-B1 | ISOCYANATE COMPOSITION, METHOD FOR PRODUCING ISOCYANATE COMPOSITION, AND METHOD FOR PRODUCING ISOCYANATE POLYMER | ASAHI CHEMICAL IND (JP) | 2025-07-23 | — | — | EP | disclosed |
| US-12351703-B2 | Cellulose ester composition and articles made therefrom | ACETATE INTERNATIONAL LLC (US) | 2025-07-08 | — | — | US | disclosed |
| EP-4558557-A1 | COMPOSITION CONTAINING CELLULOSE ESTER POLYMER WITH ENHANCED MELT STRENGTH AGENT | Celanese International Corporation (US) | 2025-05-28 | — | — | EP | disclosed |
| JP-S5598224-A | PRODUCTION OF AROMATIC POLYESTER CARBONATE | SUMITOMO CHEM CO LTD | 1980-07-26 | — | — | JP | disclosed |
| US-4137221-A | Heat-curable and solvent-soluble ester group-containing polymer compositions and process for their preparation | TEIJIN LIMITED (JP) | 1979-01-30 | — | — | US | disclosed |
| US-4115206-A | Separation of phenol-, cyclohexanone-, and cyclohexylbenzene-containing mixtures employing an organic carbonate | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4085090-A | Aromatic polymers containing a nitrogen-containing ring group, and process for preparation thereof | TEIJIN LIMITED (JA) | 1978-04-18 | — | — | US | disclosed |
| US-3946033-A | FROM GLYCINE DERIVATIVE, PRIMARY AMINE, DIARYL CARBONATE | TEIJIN LTD. (JA) | 1976-03-23 | — | — | US | disclosed |