Metolcarb

Metolcarb

SCHEMBL258226

CNC(=O)Oc1cccc(C)c1.OP(O)O

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.59
ALDH1A1 P00352 6/20 0.57
CYP3A4 P08684 2/20 0.57
MAPK1 P28482 2/20 0.57
FAAH O00519 1/20 0.57
BCHE P06276 1/20 0.51
ACHE P22303 1/20 0.51
MAPT P10636 4/20 0.47
KDM4E B2RXH2 2/20 0.47
NPC1 O15118 2/20 0.47
HPGD P15428 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
THRB P10828 1/20 0.47
CYP1A2 P05177 1/20 0.47
GAA P10253 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Metolcarb SCHEMBL29413999 0.95 LMNA (0.65) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL118244 0.95 LMNA (0.65) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL1974820 0.94 LMNA (0.56) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL8024716 0.93 LMNA (0.62) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL28786421 0.93 LMNA (0.62) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL11000289 0.93 LMNA (0.62) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL7079404 0.93 LMNA (0.62) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL11681132 0.93 LMNA (0.62) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL2150576 0.92 ALDH1A1 (0.57) LMNAALDH1A1CYP3A4MAPK1FAAH
Metolcarb SCHEMBL1879809 0.92 LMNA (0.61) LMNAALDH1A1CYP3A4MAPK1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 552 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2749629-B1 WORKING FLUID COMPOSITION FOR A REFRIGERATING MACHINE JX NIPPON OIL & ENERGY CORP (JP) 2017-04-26 EP claimed
EP-2749629-A1 Working fluid composition for a refrigerating machine Nippon Oil Corporation (JP) 2014-07-02 EP claimed
US-8193274-B2 Metal-clad laminates having improved peel strength and compositions useful for the preparation thereof ARLON (US) 2012-06-05 US claimed
EP-4711434-A1 REFRIGERANT CYCLE APPARATUS Daikin Industries, Ltd. (JP) 2026-03-18 EP disclosed
US-12534679-B2 Lubricant base oil and lubricant composition IDEMITSU KOSAN CO., LTD. (JP) 2026-01-27 US disclosed
US-12529005-B2 Lubricating oil compositions for electric vehicles CHEVRON JAPAN LTD. (JP) 2026-01-20 US disclosed
EP-4234293-B1 REFRIGERATION CYCLE DEVICE FOR VEHICLE DAIKIN IND LTD (JP) 2025-12-24 EP disclosed
US-12441922-B2 Refrigerant-containing composition, use of same, refrigerator having same, operation method for said refrigerator, and refrigeration cycle device equipped with same DAIKIN INDUSTRIES, LTD. (JP) 2025-10-14 US disclosed
EP-4433564-B1 LUBRICATING OIL COMPOSITIONS FOR ELECTRIC VEHICLES CHEVRON JAPAN LTD (JP) 2025-08-27 EP disclosed
EP-4559997-A1 LUBRICATING OIL COMPOSITION ENEOS Corporation (JP) 2025-05-28 EP disclosed
US-12291686-B2 Lubricating oil compositions for automatic transmissions CHEVRON JAPAN LTD. (JP) 2025-05-06 US disclosed
US-4251425-A Polycarbonate resin composition TEIJIN CHEMICALS, LTD. (JP) 1981-02-17 US disclosed
US-4222931-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl ether alcohol or ether, phosphonic acid ester and phenolic antioxidant ARGUS CHEMICAL CORPORATION (US) 1980-09-16 US disclosed
US-4219463-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, β-thioalkyl propionic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-08-26 US disclosed
US-4210577-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, phosphonic acid ester and phenol ARGUS CHEMICAL CORPORATION (US) 1980-07-01 US disclosed
US-4209431-A OXIDATION AND HEAT RESISTANCE WITCO CHEMICAL CORPORATION (US) 1980-06-24 US disclosed
US-4110306-A Stabilizers for synthetic polymers comprising 2,2,6,6-tetramethyl-4-piperidyl carboxylic acid ester, a triphosphite, and an acid phosphite or salt thereof ARGUS CHEMICAL CORPORATION (US) 1978-08-29 US disclosed
US-4105627-A MERCAPTOHETEROCYCLIC RESIN STABILIZERS ARGUS CHEMICAL CORPORATION (US) 1978-08-08 US disclosed
US-4080364-A Stabilization of polyolefins against degradative deterioration as a result of exposure to light and air at elevated temperatures ARGUS CHEMICAL CORPORATION (US) 1978-03-21 US disclosed
US-3997551-A OXIDATION RESISTANCE, STABILIZE POLYMERS ARGUS CHEMICAL CORPORATION (US) 1976-12-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12534679-B2 Lubricant base oil and lubricant composition INF2, F2, U2AF2 LMNA 2333/4885ALDH1A1 3652/4885CYP3A4 4510/4885
US-12529005-B2 Lubricating oil compositions for electric vehicles BRSK2, TRIB1, SCO2 LMNA 4340/4885ALDH1A1 1189/4885CYP3A4 554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.