Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CDC14B | O60729 | 1/20 | 0.31 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18798598 | 0.94 | ALOX5 (0.38) | ALOX5HSD17B1HSD17B2PLA2G2APLA2G4A | |
| SCHEMBL4083880 | 0.94 | ALOX5 (0.38) | ALOX5HSD17B1HSD17B2PLA2G2APLA2G4A | |
| SCHEMBL18101506 | 0.92 | ALOX5 (0.34) | ALOX5PLA2G2APLA2G4APGRNR3C1 | |
| SCHEMBL18798578 | 0.91 | ALOX5 (0.39) | ALOX5PGRCYP19A1NR3C1AR | |
| SCHEMBL18101583 | 0.89 | ALOX5 (0.32) | ALOX5PGRNR3C1ARMAPT | |
| SCHEMBL18101557 | 0.89 | ALOX5 (0.32) | ALOX5PGRNR3C1AR | |
| SCHEMBL18798603 | 0.87 | ALOX5 (0.38) | ALOX5PLA2G2APLA2G4APGRNR3C1 | |
| SCHEMBL20696438 | 0.87 | ALOX5 (0.36) | ALOX5CYP19A1CDC14BCDC14ACYP1A2 | |
| SCHEMBL16185357 | 0.87 | ALOX5 (0.40) | ALOX5PLA2G2APLA2G4ACYP19A1AR | |
| SCHEMBL18798574 | 0.86 | AHR (0.39) | ALOX5CYP1A2MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9640773-B2 | Aromatic amine derivative and organic electroluminescence element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-02 | — | — | US | disclosed |
| US-9640773-B2 | Aromatic amine derivative and organic electroluminescence element using same | IDEMITSU KOSAN CO., LTD. (JP) | 2017-05-02 | — | — | US | disclosed |