SCHEMBL18798588

SCHEMBL18798588

c1ccc(N(c2cc3ccc4cc(N(c5ccccc5)c5cccc6c5oc5ccccc56)cc5ccc(c2)c3c45)c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.37
AHR P35869 4/20 0.35
KDM4E B2RXH2 2/20 0.33
GAA P10253 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALPI P09923 1/20 0.33
MAPT P10636 1/20 0.33
PKM P14618 1/20 0.33
CASP3 P42574 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
CASP7 P55210 1/20 0.33
CASP6 P55212 1/20 0.33
KMT2A Q03164 1/20 0.33
MCL1 Q07820 1/20 0.33
PRKDC P78527 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18798594 0.93 ALOX5 (0.39) ALOX5AHRKDM4EGAAHPGD
SCHEMBL18798589 0.91 ALOX5 (0.35) ALOX5AHRKDM4EGAAHPGD
SCHEMBL17737654 0.90 AHR (0.39) ALOX5AHRKDM4EGAAHPGD
SCHEMBL17369938 0.90 ALOX5 (0.41) ALOX5AHRKDM4EGAAHPGD
SCHEMBL18798601 0.90 ALOX5 (0.36) ALOX5AHRKDM4EGAAHPGD
SCHEMBL18798583 0.90 GABRP (0.35) ALOX5AHRHPGDMEN1MAPT
SCHEMBL15306316 0.88 ALOX5 (0.41) ALOX5AHRKDM4EGAAHPGD
SCHEMBL14295303 0.87 ALOX5 (0.41) ALOX5AHRKDM4EGAAHPGD
SCHEMBL14295291 0.87 ALOX5 (0.40) ALOX5AHRKDM4EGAAHPGD
SCHEMBL24888363 0.86 ALOX5 (0.35) ALOX5AHRKDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9640773-B2 Aromatic amine derivative and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-05-02 US disclosed
US-9640773-B2 Aromatic amine derivative and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-05-02 US disclosed