Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24904423 | 0.76 | TRPV1 (0.43) | ALDH1A1 | |
| SCHEMBL2739665 | 0.76 | ALDH1A1 (0.38) | ALDH1A1SCN8ASCN10A | |
| SCHEMBL12463520 | 0.73 | CYP19A1 (0.39) | HRH3ALDH1A1CYP19A1 | |
| SCHEMBL18798735 | 0.72 | MAPT (0.38) | ALDH1A1 | |
| SCHEMBL18798716 | 0.72 | NPC1 (0.33) | SCN8ASCN10A | |
| SCHEMBL21740734 | 0.68 | CNR2 (0.34) | — | |
| SCHEMBL19841854 | 0.66 | POLB (0.35) | ALDH1A1 | |
| SCHEMBL14378361 | 0.65 | ALDH1A1 (0.39) | HRH3ALDH1A1CYP19A1 | |
| SCHEMBL25825172 | 0.64 | SCN10A (0.42) | ALDH1A1SCN10A | |
| SCHEMBL12395319 | 0.63 | ALDH1A1 (0.38) | HRH3ALDH1A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637491-B2 | Pyrazolo[4,3-D]pyrimidines as kinase inhibitors | ORIGENIS GMBH (DE) | 2017-05-02 | — | — | US | disclosed |