Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800449 | 0.83 | MEN1 (0.34) | EPHX2ALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL2608232 | 0.82 | ZDHHC20 (0.47) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL10157165 | 0.81 | SMN1; SMN2 (0.44) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL26897437 | 0.79 | EPHX2 (0.41) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL25083957 | 0.78 | EPHX2 (0.43) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL27376267 | 0.78 | ALDH1A1 (0.50) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL25868257 | 0.78 | EPHX2 (0.43) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL5981227 | 0.77 | EPHX2 (0.47) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL3555994 | 0.77 | EPHX2 (0.47) | EPHX2ALDH1A1TSHRL3MBTL1KMT2A | |
| SCHEMBL12313870 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9637441-B2 | Compositions containing, methods involving, and uses of non-natural amino acids and polypeptides | AMBRX, INC. (US) | 2017-05-02 | — | — | US | disclosed |