Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.35 |
| ▸ | STK10 | O94804 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18803249 | 0.91 | CNR1 (0.45) | PDK2CNR1NR1H4FFAR1FFAR4 | |
| SCHEMBL19628820 | 0.91 | PDK2 (0.43) | PDK2CNR1ALDH1A1NPSR1BRD4 | |
| SCHEMBL16366611 | 0.90 | PDK2 (0.39) | PDK2FFAR1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22182374 | 0.87 | PDK2 (0.47) | PDK2ALDH1A1TSHRMAPK1NPSR1 | |
| SCHEMBL20935760 | 0.87 | PDK2 (0.46) | PDK2CNR1ALDH1A1STK10SLK | |
| SCHEMBL29440300 | 0.87 | PDK2 (0.49) | PDK2CNR1ALDH1A1NPSR1BRD4 | |
| SCHEMBL15275876 | 0.87 | PDK2 (0.49) | PDK2CNR1ALDH1A1NPSR1BRD4 | |
| SCHEMBL22182363 | 0.87 | PDK2 (0.46) | PDK2ALDH1A1NPSR1STK10SLK | |
| SCHEMBL9916951 | 0.87 | PDK2 (0.48) | PDK2ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL16366512 | 0.87 | PDK2 (0.48) | PDK2ALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10396289-B2 | Spiro organic compounds, material comprising the same for organic electroluminescence devices, and organic electroluminescence device comprising the material | NANJING TOPTO MATERIALS CO., LTD. (CN) | 2019-08-27 | — | — | US | disclosed |
| US-20170125678-A1 | NOVEL ORGANIC COMPOUND, MATERIAL COMPRISING THE SAME FOR ORGANIC ELECTROLUMINESCENCE DEVICES, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE MATERIAL | NANJING TOPTO MATERIALS CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |
| US-20170125678-A1 | NOVEL ORGANIC COMPOUND, MATERIAL COMPRISING THE SAME FOR ORGANIC ELECTROLUMINESCENCE DEVICES, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE MATERIAL | NANJING TOPTO MATERIALS CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |
| US-20170125677-A1 | NOVEL ORGANIC COMPOUND, MATERIAL COMPRISING THE SAME FOR ORGANIC ELECTROLUMINESCENCE DEVICES, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE MATERIAL | NANJING TOPTO MATERIALS CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |
| US-20170125677-A1 | NOVEL ORGANIC COMPOUND, MATERIAL COMPRISING THE SAME FOR ORGANIC ELECTROLUMINESCENCE DEVICES, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE MATERIAL | NANJING TOPTO MATERIALS CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170125677-A1 | NOVEL ORGANIC COMPOUND, MATERIAL COMPRISING THE SAME FOR ORGANIC ELECTROLUMINESCENCE DEVICES, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE MATERIAL | SLCO4C1, PIEZO1, TRPA1 | PDK2 2700/4885CNR1 3170/4885NR1H4 3794/4885 |
| US-20170125678-A1 | NOVEL ORGANIC COMPOUND, MATERIAL COMPRISING THE SAME FOR ORGANIC ELECTROLUMINESCENCE DEVICES, AND ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE MATERIAL | OR10J3, TRPM4, PIEZO1 | PDK2 2517/4885CNR1 4796/4885NR1H4 4492/4885 |
| US-10396289-B2 | Spiro organic compounds, material comprising the same for organic electroluminescence devices, and organic electroluminescence device comprising the material | TRPA1, SLCO4C1, TRPC1 | PDK2 1334/4885CNR1 3492/4885NR1H4 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.