SCHEMBL18804653

SCHEMBL18804653

Cc1ccc(/C=N/NS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 12/20 0.72
MEN1 O00255 11/20 0.72
LMNA P02545 4/20 0.64
TDP1 Q9NUW8 3/20 0.64
KDM4E B2RXH2 2/20 0.64
ALDH1A1 P00352 9/20 0.62
MAPT P10636 4/20 0.62
NPSR1 Q6W5P4 3/20 0.62
HTT P42858 2/20 0.62
PKM P14618 1/20 0.62
POLB P06746 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
RECQL P46063 1/20 0.58
CYP1A2 P05177 1/20 0.57
CYP2C9 P11712 1/20 0.57
CRHBP P24387 1/20 0.57
CYP2C19 P33261 1/20 0.57
CRHR2 Q13324 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27596882 1.00 KMT2A (0.72) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL714847 0.94 KMT2A (0.70) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL6638949 0.94 KMT2A (0.70) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL714848 0.94 KMT2A (0.70) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL7001854 0.92 KMT2A (0.68) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL7001853 0.92 KMT2A (0.68) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL25063711 0.92 KMT2A (0.80) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL28090820 0.92 KMT2A (0.80) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL28665881 0.91 KMT2A (0.71) KMT2AMEN1LMNATDP1KDM4E
SCHEMBL28665880 0.91 KMT2A (0.71) KMT2AMEN1LMNATDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170121752-A1 DETECTION OF ACRYLIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-05-04 US disclosed
US-20170121752-A1 DETECTION OF ACRYLIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-05-04 US disclosed