Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.68 |
| ▸ | MEN1 | O00255 | 8/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RRM1 | P23921 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001854 | 1.00 | KMT2A (0.68) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL714848 | 0.98 | KMT2A (0.70) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL714847 | 0.98 | KMT2A (0.70) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL6638949 | 0.98 | KMT2A (0.70) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL28665880 | 0.93 | KMT2A (0.71) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL28665881 | 0.93 | KMT2A (0.71) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL27596882 | 0.92 | KMT2A (0.72) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL18804653 | 0.92 | KMT2A (0.72) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| Fluorobenzene SCHEMBL28187017 | 0.91 | KMT2A (0.72) | KMT2AALDH1A1MEN1TDP1KDM4E | |
| SCHEMBL25063711 | 0.90 | KMT2A (0.80) | KMT2AALDH1A1MEN1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983236-B1 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | AVECIA LTD (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-6559323-B1 | Degradation of hydrazone compound to diazo compound; catalysis with transition metal; reaction with sulfide | AVECIA LIMITED (GB) | 2003-05-06 | — | — | US | disclosed |
| EP-0983236-A2 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | Avecia Limited (GB) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998051666-A2 | PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE | AVECIA LIMITED (GB) | 1998-11-19 | — | — | WO | disclosed |