SCHEMBL714848

SCHEMBL714848

Cc1ccc(S(=O)(=O)NN=Cc2ccccc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.70
ALDH1A1 P00352 9/20 0.70
MEN1 O00255 8/20 0.70
TDP1 Q9NUW8 4/20 0.70
KDM4E B2RXH2 2/20 0.69
LMNA P02545 4/20 0.65
RECQL P46063 3/20 0.62
POLB P06746 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
MAPT P10636 4/20 0.59
PKM P14618 1/20 0.59
NPSR1 Q6W5P4 1/20 0.59
GAA P10253 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
HTT P42858 1/20 0.58
RRM1 P23921 1/20 0.58
CYP1A2 P05177 2/20 0.57
CYP2C9 P11712 2/20 0.57
CYP2C19 P33261 2/20 0.57
CYP3A4 P08684 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6638949 1.00 KMT2A (0.70) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL714847 1.00 KMT2A (0.70) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL7001854 0.98 KMT2A (0.68) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL7001853 0.98 KMT2A (0.68) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL28665880 0.94 KMT2A (0.71) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL28665881 0.94 KMT2A (0.71) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL27596882 0.94 KMT2A (0.72) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL18804653 0.94 KMT2A (0.72) KMT2AALDH1A1MEN1TDP1KDM4E
Fluorobenzene SCHEMBL28187017 0.93 KMT2A (0.72) KMT2AALDH1A1MEN1TDP1KDM4E
SCHEMBL25063711 0.92 KMT2A (0.80) KMT2AALDH1A1MEN1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591524-A Benzaldehyde p-toluenesulfonyl hydrazone and synthesis method thereof 云南贵金属实验室有限公司 2025-03-11 CN claimed
CN-115260070-A Synthesis method of beta- (N-benzaldehyde p-toluenesulfonylhydrazone) selenide 成都理工大学 2022-11-01 CN claimed
CN-107233925-B Preparation method of ruthenium carbene catalyst 中国石油化工股份有限公司 2020-04-07 CN claimed
CN-108147982-A The C-N coupling reaction techniques of the Tosylhydrazone of chemical property mutability 成都理工大学 2018-06-12 CN claimed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP claimed
EP-3965738-B1 METHOD FOR PRODUCTION OF LIPOSOMES UNIV DO MINHO (PT) 2025-08-06 EP disclosed
WO-2025136936-A1 AGONISTS OF TREM2 ACTIVITY MERCK SHARP & DOHME LLC (US) 2025-06-26 WO disclosed
CN-119591524-A Benzaldehyde p-toluenesulfonyl hydrazone and synthesis method thereof 云南贵金属实验室有限公司 2025-03-11 CN disclosed
CN-119591524-A Benzaldehyde p-toluenesulfonyl hydrazone and synthesis method thereof 云南贵金属实验室有限公司 2025-03-11 CN disclosed
CN-119591524-A Benzaldehyde p-toluenesulfonyl hydrazone and synthesis method thereof 云南贵金属实验室有限公司 2025-03-11 CN disclosed
CN-115260070-A Synthesis method of beta- (N-benzaldehyde p-toluenesulfonylhydrazone) selenide 成都理工大学 2022-11-01 CN disclosed
CN-113372275-B Synthetic method of 3, 5-diaryl-4-trifluoromethyl pyrazole derivative 温州大学 2022-09-13 CN disclosed
US-5994552-A Process for the production of substituted thiazoline-dioxetan substrates and use thereof ROCHE DIAGNOSTICS GMBH (DE) 1999-11-30 US disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed
EP-0888350-A1 AZOLOBENZAZEPINE DERIVATIVES AS NEUROLOGICALLY ACTIVE AGENTS ZENECA LIMITED (GB) 1999-01-07 EP disclosed
US-5712106-A Process for the production of substituted thiazolin-dioxetan substrates and use thereof BOEHRINGER MANNHEIM GMBH (DE) 1998-01-27 US disclosed
WO-1997032883-A1 AZOLOBENZAZEPINE DERIVATIVES AS NEUROLOGICALLY ACTIVE AGENTS ZENECA LIMITED (GB) 1997-09-12 WO disclosed
US-5455357-A Substituted thiazoline-dioxetan substrates, process for the production and use BOEHRINGER MANNHEIM GMBH (DE) 1995-10-03 US disclosed
EP-0591489-A1 SUBSTITUTED THIAZOLINE-DIOXETANE-SUBSTRATES, PROCESS FOR PRODUCING THE SAME AND THEIR USE BOEHRINGER MANNHEIM GMBH (DE) 1994-04-13 EP disclosed
WO-1993020083-A1 SUBSTITUTED THIAZOLINE-DIOXETANE-SUBSTRATES, PROCESS FOR PRODUCING THE SAME AND THEIR USE BOEHRINGER MANNHEIM GMBH (DE) 1993-10-14 WO disclosed