Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.42 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003524 | 1.00 | FFAR1 (0.53) | FFAR1FFAR4GPR84LMNAFAAH | |
| SCHEMBL28729976 | 0.93 | LMNA (0.48) | FFAR1FFAR4GPR84LMNAFAAH | |
| SCHEMBL6411243 | 0.91 | LMNA (0.46) | FFAR1FFAR4GPR84LMNAFAAH | |
| SCHEMBL17165699 | 0.88 | GPR84 (0.44) | FFAR1FFAR4GPR84LMNACAMK2A | |
| SCHEMBL22616821 | 0.88 | TSHR (0.44) | FFAR1FFAR4GPR84LMNACAMK2A | |
| SCHEMBL22589990 | 0.87 | LMNA (0.61) | FFAR1FFAR4GPR84LMNAFAAH | |
| SCHEMBL7945802 | 0.87 | LMNA (0.61) | FFAR1FFAR4GPR84LMNAFAAH | |
| SCHEMBL21807009 | 0.87 | LMNA (0.61) | LMNAFAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL13133199 | 0.87 | LMNA (0.43) | FFAR1FFAR4GPR84LMNAFAAH | |
| SCHEMBL7959647 | 0.87 | LMNA (0.61) | FFAR1FFAR4GPR84LMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | THE CURATORS OF THE UNIVERSITY OF MISSOURI | 2011-05-05 | — | — | US | disclosed |
| WO-2009158633-A1 | DRUG CONJUGATES | CURATORS OF THE UNIVERSITY OF MISSOURI ON BEHALF OF THE UNIVERSITY OF MISSOURI-KANSAS CITY (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110105417-A1 | Drug Conjugates | ABCB1, SLCO2B1, ABCG2 | FFAR1 374/4885FFAR4 368/4885GPR84 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.