Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA6 | P23280 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10705418 | 1.00 | HCAR2 (0.65) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL26342112 | 0.89 | HCAR2 (0.63) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL23343704 | 0.84 | HCAR2 (0.67) | HCAR2LMNAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL357565 | 0.84 | HCAR2 (0.89) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL337504 | 0.84 | HCAR2 (0.89) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL337503 | 0.84 | HCAR2 (0.89) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL26340997 | 0.83 | HCAR2 (0.65) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL4965299 | 0.83 | HCAR2 (0.65) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL26341007 | 0.83 | HCAR2 (0.65) | HCAR2LMNAAKR1B10AKR1B1CA12 | |
| SCHEMBL28745119 | 0.83 | HCAR2 (0.59) | HCAR2LMNAAKR1B10AKR1B1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1666440-B1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-7939674-B2 | Process for producing an aromatic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-05-10 | — | — | US | disclosed |
| US-7700642-B2 | Process for producing an aromatic unsaturated compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-30 | — | — | US | disclosed |
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-09-11 | — | — | US | disclosed |
| EP-1666440-A1 | METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
| EP-0126974-B1 | CARBOXYALKYL PEPTIDE DERIVATIVES | G.D. Searle & Co. (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4568666-A | COLLAGENASE INHIBITORS, ANTIARTJRITIC AGENTS | G. D. SEARLE & CO. (US) | 1986-02-04 | — | — | US | disclosed |
| US-4511504-A | COLLAGENASE INHIBITORS | G.D. SEARLE & CO. (US) | 1985-04-16 | — | — | US | disclosed |
| EP-0126974-A1 | Carboxyalkyl peptide derivatives | G.D. Searle & Co. (US) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221337-A1 | Process for Producing an Aromatic Unsaturated Compound | AHR, AR, ARSA | HCAR2 122/4885LMNA 788/4885AKR1B10 74/4885 |
| US-20090111999-A1 | PROCESS FOR PRODUCING AN AROMATIC UNSATURATED COMPOUND | AHR, AR, ARSA | HCAR2 122/4885LMNA 788/4885AKR1B10 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.