SCHEMBL4965299

SCHEMBL4965299

O=C(C=CC(F)(F)F)OCc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.65
LMNA P02545 2/20 0.61
AKR1B10 O60218 2/20 0.56
AKR1B1 P15121 2/20 0.56
CA12 O43570 2/20 0.56
CA4 P22748 2/20 0.56
CA6 P23280 2/20 0.56
CA5A P35218 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CA14 Q9ULX7 2/20 0.56
CA5B Q9Y2D0 2/20 0.56
TTR P02766 1/20 0.51
ALDH1A1 P00352 6/20 0.50
POLB P06746 1/20 0.50
KMT2A Q03164 2/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A3 Q01959 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26341007 1.00 HCAR2 (0.65) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL26340997 1.00 HCAR2 (0.65) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL26342112 0.89 HCAR2 (0.63) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL337504 0.84 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL337503 0.84 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL357565 0.84 HCAR2 (0.89) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL10705418 0.83 HCAR2 (0.65) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL1880576 0.83 HCAR2 (0.65) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL27659194 0.82 HCAR2 (0.85) HCAR2LMNAAKR1B10AKR1B1CA12
SCHEMBL30999857 0.80 HCAR2 (0.76) HCAR2LMNAAKR1B10AKR1B1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111406077-B Copolymers of halogenated olefins and halogenated comonomers 阿科玛股份有限公司 2024-07-05 CN disclosed
US-11725071-B2 Copolymers of halogenated olefins and halogenated co-monomers ARKEMA INC. (US) 2023-08-15 US disclosed
US-20230227589-A1 COPOLYMERS OF HALOGENATED OLEFINS AND HALOGENATED CO-MONOMERS ARKEMA INC (US) 2023-07-20 US disclosed
CN-115626961-A Polymers of haloalkyl and haloalkenyl ether (meth) acrylates 阿科玛股份有限公司 2023-01-20 CN disclosed
US-11370871-B2 Salt-tolerant star macromolecules PILOT POLYMER TECHNOLOGIES, INC. (US) 2022-06-28 US disclosed
US-20220135719-A1 POLYMERS OF HALOALKYL AND HALOALKENYL ETHER (METH)ACRYLATES ARKEMA INC (US) 2022-05-05 US disclosed
US-11254765-B2 Polymers of haloalkyl and haloalkenyl ether (meth)acrylates ARKEMA INC. (US) 2022-02-22 US disclosed
US-10941230-B2 Surfactant-compatible star macromolecules PILOT POLYMER TECHNOLOGIES, INC. (US) 2021-03-09 US disclosed
US-20200299442-A1 POLYMERS OF HALOALKYL AND HALOALKENYL ETHER (METH)ACRYLATES ARKEMA INC. 2020-09-24 US disclosed
US-20200299433-A1 COPOLYMERS OF HALOGENATED OLEFINS AND HALOGENATED CO-MONOMERS ARKEMA INC. 2020-09-24 US disclosed
EP-3164429-A1 SURFACTANT-COMPATIBLE STAR MACROMOLECULES ATRP Solutions, Inc. (US) 2017-05-10 EP disclosed
US-9587064-B2 Salt-tolerant star macromolecules ATRP Solutions, Inc. (US) 2017-03-07 US disclosed
WO-2016004357-A1 SURFACTANT-COMPATIBLE STAR MACROMOLECULES ATRP Solutions, Inc. (US) 2016-01-07 WO disclosed
US-20150376323-A1 Salt-Tolerant Star Macromolecules U.S. BANK NATIONAL ASSOCIATION, AS ADMINISTRATIVE AGENT 2015-12-31 US disclosed
EP-2951220-A1 SALT-TOLERANT STAR MACROMOLECULES ATRP Solutions, Inc. (US) 2015-12-09 EP disclosed
WO-2014121188-A1 SALT-TOLERANT STAR MACROMOLECULES ATRP Solutions, Inc. (US) 2014-08-07 WO disclosed
EP-2697275-A1 AMPHIPHOBIC BLOCK COPOLYMERS AND APPLICATIONS THEREOF Queen's University At Kingston (CA) 2014-02-19 EP disclosed
WO-2012139207-A1 AMPHIPHOBIC BLOCK COPOLYMERS AND APPLICATIONS THEREOF QUEEN'S UNIVERSITY AT KINGSTON (CA) 2012-10-18 WO disclosed
EP-1960839-A2 LOW SURFACE ENERGY BLOCK CO-POLYMER PREPARATION METHODS AND APPLICATIONS Arkema Inc. (US) 2008-08-27 EP disclosed
WO-2007078819-A2 LOW SURFACE ENERGY BLOCK CO-POLYMER PREPARATION METHODS AND APPLICATIONS ARKEMA INC. (US) 2007-07-12 WO disclosed