Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 6/20 | 0.51 |
| ▸ | FAP | Q12884 | 5/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.51 |
| ▸ | ACE | P12821 | 8/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806516 | 0.92 | PREP (0.49) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL18806509 | 0.86 | PREP (0.52) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL17345171 | 0.77 | PREP (0.70) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL18806547 | 0.75 | ACE (0.34) | ACEACE2 | |
| SCHEMBL17345293 | 0.74 | PREP (0.69) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL18806524 | 0.74 | DPP4 (0.34) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL18806486 | 0.70 | ACE (0.57) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL17345172 | 0.69 | PREP (0.58) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL24067537 | 0.69 | PREP (0.70) | PREPFAPDPP8DPP9ACE | |
| SCHEMBL29359250 | 0.68 | PREP (1.00) | PREPFAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | BACH BIOSCIENCES, LLC | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119901-A1 | FAP-ACTIVATED THERAPEUTIC AGENTS, AND USES RELATED THERETO | FAP, FIBP, FAH | PREP 61/4885FAP 1/4885DPP8 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.