Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614417 | 0.92 | APP (1.00) | APPMAOB | |
| SCHEMBL29375251 | 0.92 | APP (1.00) | APPMAOB | |
| SCHEMBL12268073 | 0.92 | APP (1.00) | APPMAOB | |
| SCHEMBL18822149 | 0.80 | APP (0.70) | APPMAOB | |
| SCHEMBL18211386 | 0.79 | APP (0.76) | APPMAOB | |
| SCHEMBL1507879 | 0.79 | APP (0.76) | APPMAOB | |
| SCHEMBL1615276 | 0.78 | APP (1.00) | APPMAOB | |
| SCHEMBL12317126 | 0.78 | APP (0.74) | APPMAOB | |
| SCHEMBL1615317 | 0.76 | APP (0.68) | APPMAOB | |
| SCHEMBL1615472 | 0.75 | APP (0.73) | APPMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170119912-A1 | PYRROLO[2,3-C]PYRIDINES AS IMAGING AGENTS FOR NEUROFIBRILLARY | MERCK SHARP & DOHME CORP. (US) | 2017-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170119912-A1 | PYRROLO[2,3-C]PYRIDINES AS IMAGING AGENTS FOR NEUROFIBRILLARY | MAPT, SNCA, PARK7 | APP 7/4885MAOB 209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.