SCHEMBL29375251

SCHEMBL29375251

Cn1ccc2cc(-c3nc4ccc(F)nc4o3)cnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
APP P05067 17/20 1.00
MAOB P27338 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268073 1.00 APP (1.00) APPMAOB
SCHEMBL1614417 1.00 APP (1.00) APPMAOB
SCHEMBL18806907 0.92 APP (1.00) APPMAOB
SCHEMBL18211386 0.86 APP (0.76) APPMAOB
SCHEMBL1507879 0.86 APP (0.76) APPMAOB
SCHEMBL12317126 0.85 APP (0.74) APPMAOB
SCHEMBL1615276 0.83 APP (1.00) APPMAOB
SCHEMBL18822149 0.82 APP (0.70) APPMAOB
SCHEMBL1508028 0.81 APP (0.69) APP
SCHEMBL1615317 0.81 APP (0.68) APPMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651876-A1 TARGETED THERANOSTIC AGENTS FOR IMAGING AND TREATING CANCER The Board of Regents of the University of Texas System (US) 2025-11-26 EP disclosed
US-12258355-B2 Probes for imaging huntingtin protein CHDI FOUNDATION, INC. (US) 2025-03-25 US disclosed
WO-2024211430-A2 METHODS AND COMPOSITIONS FOR TREATING NEURODEGENERATIVE CONDITIONS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-10-10 WO disclosed
CN-115645389-B Application of compound ML1 and derivative thereof in improving activity and function of cerebral cortex 刘晓栋 2024-10-01 CN disclosed
WO-2024155993-A1 TARGETED THERANOSTIC AGENTS FOR IMAGING AND TREATING CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-25 WO disclosed
CN-118005611-A Probes for imaging huntingtin CHDI基金会股份有限公司 2024-05-10 CN disclosed
US-20240009332-A1 COMPOSITE EMBOLIZATION BEADS TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC 2024-01-11 US disclosed
US-11851446-B2 Probes for imaging Huntingtin protein CHDI FOUNDATION, INC. (US) 2023-12-26 US disclosed
CN-116655618-A Probes for imaging huntingtin CHDI基金会股份有限公司 2023-08-29 CN disclosed
US-20230243811-A1 IDENTIFICATION OF TRANSPLANTED HUMAN CELLS RIGSHOSPITALET (REGH) (DK) 2023-08-03 US disclosed
US-11712487-B2 Composite embolization beads RAIKA MEDICAL IMAGING INC. (US) 2023-08-01 US disclosed
US-20230212190-A1 PROBES FOR IMAGING HUNTINGTIN PROTEIN CHDI FOUNDATION, INC. 2023-07-06 US disclosed
CN-107108534-B Probes for imaging huntingtin CHDI基金会股份有限公司 2023-05-09 CN disclosed
CN-115645389-A Application of compound ML1 and derivatives thereof in improving activity and function of cerebral cortex 刘晓栋 2023-01-31 CN disclosed
EP-3166610-B1 METHODS FOR TREATING NEUROLOGIC DISORDERS EIP PHARMA LLC (US) 2022-11-02 EP disclosed
EP-3368040-B1 METHODS AND COMPOSITIONS FOR RECOVERY FROM STROKE EIP PHARMA LLC (US) 2022-08-17 EP disclosed
EP-4006016-A2 PROBES FOR IMAGING HUNTINGTIN PROTEIN CHDI Foundation, Inc. (US) 2022-06-01 EP disclosed
US-11344637-B2 Probes for imaging huntingtin protein CHDI FOUNDATION, INC. (US) 2022-05-31 US disclosed
US-11291670-B2 Therapeutic approaches for treating Alzheimer disease and related disorders through a modulation of angiogenesis PHARNEXT (FR) 2022-04-05 US disclosed
CN-114010641-A Methods for treating neurological disorders 爱普制药有限责任公司 2022-02-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851446-B2 Probes for imaging Huntingtin protein HTT, HYPK, HSPBP1 APP 270/4885MAOB 3619/4885
US-20230212190-A1 PROBES FOR IMAGING HUNTINGTIN PROTEIN HTT, HYPK, HSPBP1 APP 270/4885MAOB 3619/4885
US-11344637-B2 Probes for imaging huntingtin protein HTT, HYPK, HSPBP1 APP 270/4885MAOB 3619/4885
US-12258355-B2 Probes for imaging huntingtin protein HTT, HYPK, HSPBP1 APP 270/4885MAOB 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.