Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.42 |
| ▸ | RELA | Q04206 | 5/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714510 | 0.71 | NFKB1 (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL21278609 | 0.70 | NFKB1 (0.55) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL18575676 | 0.70 | GAA (0.43) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL28931534 | 0.69 | EPHX2 (0.46) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL763965 | 0.69 | NFKB1 (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL21294876 | 0.69 | NFKB1 (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL20063806 | 0.69 | NFKB1 (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL458573 | 0.69 | BTK (0.51) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL4270314 | 0.69 | NFKB1 (0.49) | GAANFKB1NFKB2RELAEPHX2 | |
| SCHEMBL4270316 | 0.69 | NFKB1 (0.49) | GAANFKB1NFKB2RELAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735319-B1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC (CA) | 2017-05-03 | — | — | EP | disclosed |