Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914756 | 0.89 | DHODH (0.47) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL17914707 | 0.87 | DHODH (0.50) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL15595212 | 0.84 | TDP1 (0.69) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL17914714 | 0.83 | DHODH (0.46) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL17300199 | 0.83 | MEN1 (0.57) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL17914998 | 0.83 | LMNA (0.49) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL17300248 | 0.83 | CYP1B1 (0.47) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL22048782 | 0.82 | NUDT1 (0.48) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL17914745 | 0.81 | MEN1 (0.55) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 | |
| SCHEMBL17915001 | 0.81 | MEN1 (0.55) | TDP1KDM4EALDH1A1ADORA2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162797-A1 | POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME | Heesung Material Ltd. (KR) | 2017-05-03 | — | — | EP | disclosed |