Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16133790 | 0.88 | CYP3A4 (0.39) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL18809302 | 0.87 | ALDH1A1 (0.38) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL18809185 | 0.86 | CYP3A4 (0.36) | CYP3A4CYP2C8 | |
| SCHEMBL18809159 | 0.86 | CNR1 (0.38) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL19262430 | 0.84 | CYP3A4 (0.38) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL16133808 | 0.83 | CYP3A4 (0.42) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL16133764 | 0.82 | CYP3A4 (0.37) | CYP3A4CYP2C8 | |
| SCHEMBL19262422 | 0.81 | CYP3A4 (0.38) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL18809181 | 0.80 | CYP3A4 (0.38) | CYP3A4CYP2C8KCNH2 | |
| SCHEMBL2840803 | 0.80 | CYP3A4 (0.45) | CYP3A4CYP2C8KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9738653-B2 | Fused furans for the treatment of hepatitis C | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-08-22 | — | — | US | disclosed |
| EP-2970174-B1 | FUSED FURANS FOR THE TREATMENT OF HEPATITIS C | BRISTOL MYERS SQUIBB CO (US) | 2017-05-03 | — | — | EP | disclosed |