Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23702487 | 1.00 | SPHK2 (0.36) | SPHK2SPHK1L3MBTL1POLBHTT | |
| SCHEMBL14509632 | 0.88 | OPRD1 (0.42) | SPHK2SPHK1L3MBTL1POLBADRA1D | |
| SCHEMBL3429567 | 0.83 | SPHK2 (0.47) | SPHK2SPHK1L3MBTL1POLBHTT | |
| SCHEMBL3427098 | 0.83 | SPHK2 (0.47) | SPHK2SPHK1L3MBTL1POLBHTT | |
| SCHEMBL14509625 | 0.83 | ALOX15 (0.35) | SPHK2SPHK1HTTADRA1DADRA1A | |
| SCHEMBL3431942 | 0.83 | SPHK2 (0.47) | SPHK2SPHK1L3MBTL1POLBHTT | |
| SCHEMBL14509635 | 0.82 | TSHR (0.33) | SPHK2SPHK1L3MBTL1POLBADRA1D | |
| SCHEMBL6636120 | 0.81 | S1PR1 (0.41) | SPHK2SPHK1L3MBTL1POLBHTT | |
| SCHEMBL3429565 | 0.79 | POLB (0.39) | SPHK2SPHK1L3MBTL1POLBHTT | |
| SCHEMBL12067113 | 0.79 | SPHK2 (0.42) | SPHK2SPHK1L3MBTL1POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323651-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | Summit Corporation Plc (GB) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010015815-A2 | COMPOUNDS FOR THE TREATMENT OF FLAVIVIRAL INFECTIONS | SUMMIT CORPORATION PLC (GB) | 2010-02-11 | — | — | WO | disclosed |
| US-7211116-B2 | Hair dye composition | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |
| US-7211116-B2 | Hair dye composition | KAO CORPORATION (JP) | 2007-05-01 | — | — | US | disclosed |