SCHEMBL1880947

SCHEMBL1880947

Oc1ccc(CC(c2ccccc2)(c2ccccc2)c2ccc(O)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 10/20 0.53
ESR2 Q92731 9/20 0.53
ALDH1A1 P00352 1/20 0.52
CYP3A4 P08684 1/20 0.52
KIF11 P52732 3/20 0.50
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
CYP19A1 P11511 1/20 0.45
FNTA P49354 1/20 0.44
FNTB P49356 1/20 0.44
BLM P54132 1/20 0.43
MDM4 O15151 1/20 0.41
MDM2 Q00987 1/20 0.41
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
GLA P06280 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11139797 1.00 ESR1 (0.53) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL8520412 0.98 ESR1 (0.50) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL69287 0.96 KIF11 (0.54) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL156830 0.91 ESR1 (0.61) ESR1ESR2CYP3A4BLMCA2
Phenol SCHEMBL28598393 0.89 CYP1A2 (0.54) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL126749 0.82 CYP2C9 (0.58) CYP3A4KIF11CYP1A2CYP2C9CYP2C19
SCHEMBL11699396 0.82 ESR1 (0.57) ESR1ESR2ALDH1A1CYP3A4CYP2C9
SCHEMBL9972713 0.81 ESR1 (0.46) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL2416999 0.80 ESR1 (0.60) ESR1ESR2ALDH1A1CYP3A4KIF11
SCHEMBL30797203 0.80 CYP2C9 (0.56) CYP3A4KIF11CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732168-B2 Method of preparing ethylene polymers by controlled high pressure polymerization BASF SE (DE) 2017-08-15 US disclosed
EP-1891142-B1 OLIGO- AND POLY-CARBONATES TERMINATED WITH SILICON CONTAINING GROUPS AS SURFACE MODIFIERS CIBA HOLDING INC (CH) 2014-12-03 EP disclosed
US-20130150542-A1 Method Of Preparing Ethylene Polymers By Controlled High Pressure Polymerization BASF SE (DE) 2013-06-13 US disclosed
US-8013047-B2 Oligo- and poly-carbonates terminated with silicon containing groups as surface modifiers BASF SE Ludwigshafen (DE) 2011-09-06 US disclosed
US-7947767-B2 Electret materials BASF SE (DE) 2011-05-24 US disclosed
US-7790807-B2 polycarbonate endcapped with perfluoroalkanol (Zonyl\") incorporated into a polyester, polyacrylate, polymethacrylate or polypropylene via extrusion; self cleaning; antisoiling, oil resistance, solvent resistance, chemical resistance, scratch resistance, hydrophobic; molding material CIBA SPECIALTY CHEMICALS CORP. (US) 2010-09-07 US disclosed
US-20100210800-A1 METHOD OF PREPARING ETHYLENE POLYMERS BY CONTROLLED HIGH PRESSURE POLYMERIZATION CIBA CORPORATION (US) 2010-08-19 US disclosed
US-20100112886-A1 Electret Materials BASF SE (DE) 2010-05-06 US disclosed
US-7666931-B2 Electret materials CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-02-23 US disclosed
US-20100010135-A1 Oligo-and poly-carbonates terminated with silicon containing groups as surface modifiers CIBA SPECIALTY CHEMICALS CORPORATION 2010-01-14 US disclosed
WO-1999055772-A1 INCREASING THE MOLECULAR WEIGHT OF POLYESTERS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-11-04 WO disclosed
EP-0880553-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES Ciba SC Holding AG (CH) 1998-12-02 EP disclosed
US-5807932-A USING A HYDROXYPHENYLALKYLPHOSPHORIC ESTER CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-09-15 US disclosed
US-5763512-A COMPOSITION CONTAINING MIXTURE OF SPECIFIED PHOSPHITE AND HINDERED PHENOL STABILIZERS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-09 US disclosed
WO-1997030105-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1997-08-21 WO disclosed
EP-0785967-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES Ciba SC Holding AG (CH) 1997-07-30 EP disclosed
WO-1996011978-A1 INCREASING THE MOLECULAR WEIGHT OF POLYCONDENSATES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1996-04-25 WO disclosed
EP-0488190-B1 Process for producing powder aggregate particle of high molecular weight polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 1996-02-07 EP disclosed
US-5182363-A Adding poor solvent to solution, pouring into heated water, suspension, distillation, recycling slurry to wet-process pulverizer while further distilling MITSUBISHI GAS CHEMICAL CO., INC. (JP) 1993-01-26 US disclosed
EP-0488190-A1 Process for producing powder aggregate particle of high molecular weight polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1992-06-03 EP disclosed